Evidence map›Paper›PMID 35548064›Full record

ArticlePharmacogenomics and personalized medicine2022

Susceptibility of Genetic Variations in Methylation Pathway to Gastric Cancer.

Mengqiu Xiong, Bei Pan, Xuhong Wang, Junjie Nie, Yuqin Pan, Huiling Sun, Tao Xu, William C S Cho, Shukui Wang, Bangshun He

Open access · goldAbstract read
In one paragraph

Article in Pharmacogenomics and personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Mengqiu Xiong *Clinical Laboratory, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, People's Republic of China.
Bei Pan *Medical College, Southeast University, Nanjing, 210006, People's Republic of China.
Xuhong WangMedical College, Southeast University, Nanjing, 210006, People's Republic of China.
Junjie NieClinical Laboratory, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, People's Republic of China.
Yuqin PanClinical Laboratory, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, People's Republic of China.
Huiling SunClinical Laboratory, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, People's Republic of China.
Tao XuClinical Laboratory, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, People's Republic of China.
William C S ChoDepartment of Clinical Oncology, Queen Elizabeth Hospital, Hongkong SAR, People's Republic of China.ORCID 0000-0003-4174-4586
Shukui WangClinical Laboratory, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, People's Republic of China.
Bangshun HeClinical Laboratory, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, People's Republic of China.ORCID 0000-0001-7812-6197
Nanjing Medical University · CNSoutheast University · CNQueen Elizabeth Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: DNA methylation in the CpG island is associated with gastric cancer, genetic variations residue in genes involved in methylation pathway could contribute to the occurrence of gastric cancer. Here, we investigated the association between Patients and Methods: We recruited 490 gastric cancer patients and 488 age- and sex-matched healthy controls. The genotypes of the genetic variations were detected by a Mass-array platform. A commercial Results: We found that carriers of Conclusion: We concluded that the

Indexed as

DNMTsgastric cancergenetic variationMTHFR

Identifiers

PMID35548064
PMCPMC9081620
OpenAlexW4225408338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.