Evidence map›Paper›PMID 35547854›Full record

ArticlemedRxiv : the preprint server for health sciences2022

Partial ORF1ab Gene Target Failure with Omicron BA.2.12.1.

Kyle G Rodino, David R Peaper, Brendan J Kelly, Frederic Bushman, Andrew Marques, Hriju Adhikari, Zheng Jin Tu, Rebecca Marrero Rolon, Lars F Westblade, Daniel A Green and 13 more

Open access · greenAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 7 institutions in 1 country.

Kyle G Rodino
David R Peaper
Brendan J Kelly
Andrew Marques
Hriju Adhikari
Zheng Jin Tu
Rebecca Marrero Rolon
Lars F Westblade
Daniel A Green
Gregory J Berry
Fann Wu
Medini K Annavajhala
Anne-Catrin Uhlemann
Bijal A Parikh
Tracy McMillen
Krupa Jani
N Esther Babady
Anne M Hahn
Robert T Koch
Nathan D Grubaugh
Yale SARS-CoV-2 Genomic Surveillance Initiative
Daniel D Rhoads
Columbia University Irving Medical Center · USUniversity of Pennsylvania · USYale University · USCleveland Clinic · USMemorial Sloan Kettering Cancer Center · USCornell University · USWashington University in St. Louis · US

Funding

NIAID NIH HHS L30 AI120149
6 · The paper itself

Abstract

Mutations in the viral genome of SARS-CoV-2 can impact the performance of molecular diagnostic assays. In some cases, such as S gene target failure, the impact can serve as a unique indicator of a particular SARS-CoV-2 variant and provide a method for rapid detection. Here we describe partial ORF1ab gene target failure (pOGTF) on the cobas

Identifiers

PMID35547854
PMCPMC9094110
OpenAlexW4225107233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.