Evidence map›Paper›PMID 35547851›Full record

ArticleResearch square2022

CNBP restricts SARS-CoV2 by regulating IFN and disrupting RNA-protein condensates.

Katherine Fitzgerald, Yongzhi Chen, Xuqiu Lei, Zhaozhao Jiang, Fiachra Humphries, Nicholas Mustone, Irene Ramos, Tinaye Mutetwa, Ana Fernandez-Sesma

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Katherine FitzgeraldUniversity of Massachusetts Medical School.ORCID 0000-0003-3175-609X
Yongzhi ChenUniversity of Massachusetts Medical School.
Xuqiu LeiUniversity of Massachusetts Medical School.ORCID 0000-0003-3565-6969
Zhaozhao JiangUniversity of Massachusetts Medical School.
Fiachra HumphriesUMass Chan Medical School.ORCID 0000-0003-0216-5776
Nicholas MustoneUniversity of Massachusetts Medical School.
Irene RamosIcahn School of Medicine at Mount Sinai.ORCID 0000-0002-0223-0120
Tinaye MutetwaIcahn School of Medicine at Mount Sinai.
Ana Fernandez-SesmaIcahn School of Medicine at Mount Sinai.ORCID 0000-0002-3405-6702
University of Massachusetts Chan Medical School · USIcahn School of Medicine at Mount Sinai · US

Funding

Innate Immune Activation in MalariaR01AI079293 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FITZGERALD, KATHERINE A., GOLENBOCK, DOUGLAS T · 2009 to 2024
$10.9M
Gene Regulation in Innate ImmunityR37AI067497 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FITZGERALD, KATHERINE A. · 2015 to 2024
$4.6M
Regulation of Type I Interferon Gene Expression in the Innate Immune ResponseR01AI067497 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FITZGERALD, KATHERINE A. · 2006 to 2010
$2.0M
Regulation of Type I Interferon Gene Expression in the Innate Immune ResponseR56AI067497 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI FITZGERALD, KATHERINE A. · 2012 to 2012
$415k
NIAID NIH HHS R01 AI067497NIAID NIH HHS R01 AI079293NIAID NIH HHS R37 AI067497NIAID NIH HHS R56 AI067497
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evades antiviral immunity through the expression of viral proteins that block detection, signaling, interferon (IFN) induction, and IFN-stimulated gene (ISG) expression

Identifiers

PMID35547851
PMCPMC9094105
OpenAlexW4225266580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.