Evidence map›Paper›PMID 35547761›Full record

ArticleTheranostics2022

Critical role of FPR1 in splenocyte migration into brain to worsen inflammation and ischemic brain injury in mice.

Jun Li, Mahendra D Chordia, Yi Zhang, Hui Zong, Dongfeng Pan, Zhiyi Zuo

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The spleen-brain axis in Alzheimer's disease and related dementias: Integrating immune and metabolic regulation.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  7. FPR1-dependent Pro-inflammatory Ccl4Respiratory research · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jun LiDepartment of Anesthesiology, University of Virginia, Charlottesville, Virginia 22908, USA.
Mahendra D ChordiaDepartment of Radiology and Biomedical Imaging, University of Virginia, Charlottesville, VA, 22908, USA.
Yi ZhangDepartment of Radiology and Biomedical Imaging, University of Virginia, Charlottesville, VA, 22908, USA.
Hui ZongDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA, USA.
Dongfeng PanDepartment of Radiology and Biomedical Imaging, University of Virginia, Charlottesville, VA, 22908, USA.
Zhiyi ZuoDepartment of Anesthesiology, University of Virginia, Charlottesville, Virginia 22908, USA.
University of Virginia · US

Funding

Role of carboxyl-terminal modulator protein in autophagy and senescence of human induced pluripotent stem cellsRF1AG061047 · NIA · UNIVERSITY OF VIRGINIA · PI WENKER, IAN CHRISTOPHER · 2019 to 2023
$2.4M
Obesity-induced cerebral vascular remodeling and poor brain ischemic toleranceR01NS099118 · NINDS · UNIVERSITY OF VIRGINIA · PI ZUO, ZHIYI · 2018 to 2022
$1.7M
Glial cell line-derived neurotropic factor and postoperative cognitive impairment in young ratsR01HD089999 · NICHD · UNIVERSITY OF VIRGINIA · PI ZUO, ZHIYI · 2017 to 2021
$1.7M
Postoperative cognitive dysfunction and enriched environmentR21AG056995 · NIA · UNIVERSITY OF VIRGINIA · PI ZUO, ZHIYI · 2017 to 2018
$443k
NIA NIH HHS R21 AG056995NIA NIH HHS RF1 AG061047NICHD NIH HHS R01 HD089999NINDS NIH HHS R01 NS099118
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain InjuriesBrain IschemiaIschemic StrokeAnimalsBrainCytokinesInflammationMiceMice, Inbred C57BLReceptors, Formyl PeptideSpleenCytokinesFpr1 protein, mouseReceptors, Formyl PeptideBrain imagingbrain ischemiaformyl peptide receptor 1neuroinflammationneuroprotectionsplenocyte migration

Identifiers

PMID35547761
PMCPMC9065176
OpenAlexW4225889273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.