SynthesisFrontiers in aging neuroscience2022
Effectiveness and Success Factors of Bilateral Arm Training After Stroke: A Systematic Review and Meta-Analysis.
Synthesis in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Effect of exercise-based interventions on stroke rehabilitation: an umbrella review of systematic reviews and meta-analyses.Journal of neuroengineering and rehabilitation · 2025Pooled it
- Usability and effectiveness of a novel bilateral upper limb training device for stroke patients with hemiparesis: a pilot randomized controlled study.Journal of neuroengineering and rehabilitation · 2026Trial
- Investigating the correlation between neural and muscular activities during bilateral arm training in stroke survivors: A cross-sectional study.Neural regeneration research · 2026Article
- Effectiveness of Bilateral Arm Training on Upper Limb Functional Mobility in Stroke Survivors.Cureus · 2026Article
- Neuroplasticity mechanisms of NDBIs in autism: a review from brain connectivity to behavioral improvement.European journal of medical research · 2026Review
- Recommendations for Combining Brain-Computer Interface, Motor Imagery, and Virtual Reality in Upper Limb Stroke Rehabilitation: Qualitative Participatory Design Study.JMIR rehabilitation and assistive technologies · 2025Article
- Post-Stroke Rehabilitation: Neurophysiology Processes of Bilateral Movement Training and Interlimb Coupling-A Systematic Review.Journal of clinical medicine · 2025Review
- Article
- Experience-driven competition in neural reorganization after stroke.The Journal of physiology · 2025Review
- Effective unilateral/bilateral robot-assisted training for upper limb motor function rehabilitation: a cross-sectional study.Frontiers in human neuroscience · 2025Article
- The Effectiveness of Thermal Stimulation Plus Conventional Therapy for Functional Recovery After Stroke: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Feasibility and efficacy of an early sensory-motor rehabilitation program on hand function in patients with stroke: a pilot, single-subject experimental design.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Cortical activity in patients with high-functioning ischemic stroke during the Purdue Pegboard Test: insights into bimanual coordinated fine motor skills with functional near-infrared spectroscopy.Neural regeneration research · 2024Article
- Impact of Focal Muscle Vibration on Flaccid Upper Limb Motor Paralysis following Acute Brain Disease: A Case Study.Case reports in neurological medicine · 2024Article
- Bilateral versus unilateral upper limb training in (sub)acute stroke: A systematic and meta-analysis.The South African journal of physiotherapy · 2024Review
- Editorial: Rehabilitation for somatosensory disorders.Frontiers in neuroscience · 2024Article
- Home-based upper limb stroke rehabilitation mechatronics: challenges and opportunities.Biomedical engineering online · 2023Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bilateral arm training (BAT) presents as a promising approach in upper extremity (UE) rehabilitation after a stroke as it may facilitate neuroplasticity. However, the effectiveness of BAT is inconclusive, and no systematic reviews and meta-analyses have investigated the impact of different factors on the outcomes of BAT. This systematic review and meta-analysis aimed to (1) compare the effects of bilateral arm training (BAT) with unilateral arm training (UAT) and conventional therapy (CT) on the upper limb (UL) motor impairments and functional performance post-stroke, and (2) investigate the different contributing factors that may influence the success of BAT. A comprehensive literature search was performed in five databases. Randomized control trials (RCTs) that met inclusion criteria were selected and assessed for methodological qualities. Data relating to outcome measures, characteristics of participants (stroke chronicity and severity), and features of intervention (type of BAT and dose) were extracted for meta-analysis. With 25 RCTs meeting the inclusion criteria, BAT demonstrated significantly greater improvements in motor impairments as measured by Fugl-Meyer Assessment of Upper Extremity (FMA-UE) than CT (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.