ArticleCureus2022
Effect of C-Reactive Protein-to-Albumin Ratio on Prognosis in Gastric Cancer Patients.
Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Prognostic and clinicopathological value of the controlling nutritional status score in patients with multiple myeloma: a meta-analysis.Frontiers in oncology · 2025Pooled it
- Prognostic and clinicopathological significance of systemic inflammation response index in patients with hepatocellular carcinoma: a systematic review and meta-analysis.Frontiers in immunology · 2024Pooled it
- A PET-Derived SUVmax-to-Albumin Ratio Predicts Recurrence After Neoadjuvant FLOT in Gastric Cancer.Medicina (Kaunas, Lithuania) · 2026Article
- Postoperative malnutrition predicts severe chemotherapy toxicity after gastrectomy: evaluation of an inflammation-anemia phenotype.Open medicine (Warsaw, Poland) · 2026Article
- Prognostic utility of the C-reactive protein-albumin-lymphocyte (CALLY) index in metastatic renal cell carcinoma.BMC cancer · 2025Article
- Association of Systemic Inflammatory Response Index and Prognostic Nutritional Index Scores with Sarcopenia in Patients with Metastatic Gastric Cancer.Medicina (Kaunas, Lithuania) · 2025Article
- Predictive value of the preoperative C-reactive protein-to-albumin ratio for surgical site infection after percutaneous kyphoplasty: a single-center retrospective study.Frontiers in cellular and infection microbiology · 2025Article
- The Value of Preoperative C-Reactive Protein to Albumin Ratio as a Prognostic Biomarker in Colon Cancer Patients.Medicina (Kaunas, Lithuania) · 2024Observational
- Prognostic significance of the hs-CRP/Alb ratio for cardiovascular events in patients with end-stage renal disease undergoing maintenance hemodialysis.American journal of translational research · 2024Article
- Serum C-reactive protein to albumin ratio as a potential risk indicator of pneumonia caused byFrontiers in cellular and infection microbiology · 2024Article
- C-reactive protein-to-albumin ratio as a biomarker in patients with sepsis: a novel LASSO-COX based prognostic nomogram.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe ratio of c-reactive protein-to-albumin (CRP/Alb) is a biochemical marker of systemic inflammatory response and has been associated with poor survival in cancer. The purpose of this study was to investigate the effect of CRP/Alb ratios on prognosis in gastric cancers.
methodsThis study included a retrospective review of a total of 147 patients with locally advanced gastric cancer. Mean platelet volume (MPV) was analyzed statistically to find a prognostic relationship between monocyte/lymphocyte ratio, platelet distribution volume (PDW), MPV/platelet, c-reactive protein/albumin ratio (CAR), and gastric cancer. Patients were staged according to the American Joint Cancer Committee (AJCC) Staging Guidelines.
resultsThe CRP/Alb ratio was independently associated with overall survival (OS) in patients with gastric cancer (GC). The CAR was above 0.25 in 52.7% (77) of the patients and below 0.25 in 47.3% (69) of the patients. Patients under 0.25 had statistically longer survival rates.
conclusionA high preoperative CAR value could predict poor prognosis in locally advanced gastric patients. The same predictive value was not observed in other hematological parameters. This simple and cost-effective ratio can be used as a clinically accessible biomarker to assist clinicians in determining future treatment plans.
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