Evidence map›Paper›PMID 35547412›Full record

ArticleCureus2022

Antiphospholipid Syndrome in a Patient With Autosomal Dominant Polycystic Kidney Disease: The Surface of the Moon.

John Dayco, Shahzana Shahzad, Hanna Tran, Mohammed Ali, Mahmoud M Musa, Rashid Alhusain, Abdalaziz M Awadelkarim, Navid Mahabadi, Shaheena Raheem, Aris Urbanes

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Infertility and Auto-Antibodies: A Review.Antibodies (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

John DaycoInternal Medicine, Wayne State University/Detroit Medical Center, Detroit, USA.
Shahzana ShahzadInternal Medicine, Wayne State University/Detroit Medical Center, Detroit, USA.
Hanna TranInternal Medicine, Wayne State University School of Medicine, Detroit, USA.
Mohammed AliInternal Medicine, Wayne State University/Detroit Medical Center, Detroit, USA.
Mahmoud M MusaInternal Medicine, Wayne State University/Detroit Medical Center, Detroit, USA.
Rashid AlhusainInternal Medicine, Wayne State University/Detroit Medical Center, Detroit, USA.
Abdalaziz M AwadelkarimInternal Medicine, Wayne State University/Detroit Medical Center, Detroit, USA.
Navid MahabadiInternal Medicine, Wayne State University/Detroit Medical Center, Detroit, USA.
Shaheena RaheemInternal Medicine, Wayne State University/Detroit Medical Center, Detroit, USA.
Aris UrbanesInternal Medicine, Wayne State University/Detroit Medical Center, Detroit, USA.
Detroit Medical Center · USWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antiphospholipid syndrome (APS) is a rare coagulopathic disorder diagnosed with a combination of clinical/imaging findings with specific antibody titer elevations over a period of 12 weeks. The following case report will discuss the unusual and challenging hospital course of a patient with extensive autosomal dominant polycystic kidney disease (ADPKD) being treated for a multi-drug resistant urinary tract infection (UTI). The patient later developed multiple deep vein thrombosis (DVT) and was found to have antiphospholipid syndrome. Warfarin, the anticoagulant of choice for antiphospholipid syndrome, has a higher likelihood of intracerebral hemorrhage than direct oral anticoagulants. This is particularly challenging since patients with autosomal dominant polycystic kidney disease have a higher propensity to develop intracranial aneurysms (ICA).

Indexed as

auto immuneautosomal-dominant polycystic kidney diseasecomplicated urinary tract infectiondeep vein thrombosis (dvt)fever of unkown

Identifiers

PMID35547412
PMCPMC9090140
OpenAlexW4223517116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.