Evidence map›Paper›PMID 35547355›Full record

ArticleBioMed research international2022

Clinical, Serological, and Genetic Characteristics of a Hungarian Myositis-Scleroderma Overlap Cohort.

Katalin Szabó, Levente Bodoki, Melinda Nagy-Vincze, Tibor Béldi, Anett Vincze, Erika Zilahi, József Varga, Gabriella Szűcs, Katalin Dankó, Zoltán Griger

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Katalin SzabóDivision of Clinical Immunology, Faculty of Medicine, University of Debrecen, Móricz Zs. krt. 22, 4032 Debrecen, Hungary.ORCID https://orcid.org/0000-0002-0617-1703
Levente BodokiDivision of Rheumatology, Faculty of Medicine, University of Debrecen, Móricz Zs. krt. 22, 4032 Debrecen, Hungary.ORCID https://orcid.org/0000-0002-4934-6032
Melinda Nagy-VinczeDivision of Clinical Immunology, Faculty of Medicine, University of Debrecen, Móricz Zs. krt. 22, 4032 Debrecen, Hungary.ORCID https://orcid.org/0000-0003-0316-3828
Tibor BéldiDivision of Clinical Immunology, Faculty of Medicine, University of Debrecen, Móricz Zs. krt. 22, 4032 Debrecen, Hungary.ORCID https://orcid.org/0000-0003-4972-1370
Anett VinczeDivision of Clinical Immunology, Faculty of Medicine, University of Debrecen, Móricz Zs. krt. 22, 4032 Debrecen, Hungary.ORCID https://orcid.org/0000-0003-3654-9268
Erika ZilahiDepartment of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Nagyerdei krt. 98, 4032 Debrecen, Hungary.ORCID https://orcid.org/0000-0002-7376-8921
József VargaDepartment of Medical Imaging, Division of Nuclear Medicine, University of Debrecen, Debrecen, Hungary.ORCID https://orcid.org/0000-0001-5797-9625
Gabriella SzűcsDivision of Rheumatology, Faculty of Medicine, University of Debrecen, Móricz Zs. krt. 22, 4032 Debrecen, Hungary.ORCID https://orcid.org/0000-0002-0958-9531
Katalin DankóDivision of Clinical Immunology, Faculty of Medicine, University of Debrecen, Móricz Zs. krt. 22, 4032 Debrecen, Hungary.ORCID https://orcid.org/0000-0002-8729-3947
Zoltán GrigerDivision of Clinical Immunology, Faculty of Medicine, University of Debrecen, Móricz Zs. krt. 22, 4032 Debrecen, Hungary.ORCID https://orcid.org/0000-0002-1371-7911
University of Debrecen · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overlap myositis is a distinct subgroup of idiopathic inflammatory myositis (IIM) with various clinical phenotypes. The aim of this study was to determine the clinical, serological, and genetic features of systemic sclerosis (SSc)-IIM overlap patients. It was a retrospective study using clinical database of 39 patients, fulfilling both the criteria of SSc and IIM. 56.4% of the patients had limited cutaneous, 43.6% had diffuse cutaneous SSc, whereas 7.7% of the patients had dermatomyositis and 92.3% polymyositis. The two diseases occurred simultaneously in 58.97%, while 10.26% in myositis and 30.77% in scleroderma were initially diagnosed. The frequencies of organ involvement were interstitial lung disease 71.8%, dysphagia 66.7%, cardiac involvement 41%, pulmonary arterial hypertension (PAH) 30.8%, and renal involvement 12.8%, respectively. The presence of human leukocyte antigen (HLA) - DRB1∗03 and DQA1∗051∗01 alleles were significantly higher in the overlap patients than in healthy controls (82.35% vs. 27.54%;

Indexed as

Deglutition DisordersMyositisScleroderma, LocalizedScleroderma, SystemicHLA-DRB1 ChainsHumansHungaryRetrospective StudiesHLA-DRB1 Chains

Identifiers

PMID35547355
PMCPMC9085307
OpenAlexW4225273902

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.