ArticleFrontiers in microbiology2022
Selective Maternal Seeding and Rearing Environment From Birth to Weaning Shape the Developing Piglet Gut Microbiome.
Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Dietary Supplementation With Oil and Leucine Enhance the Gut Microbiota and Barrier of Offspring During Late Gestation and Lactation of Sows.Journal of animal physiology and animal nutrition · 2026Article
- Effect of Limosilactobacillus reuteri SBC5-3 Cell-free Supernatant on Growth Performance, Intestinal Inflammation, and Microbiota in Weaned Piglets Challenged With Enterotoxigenic Escherichia coli K88.Probiotics and antimicrobial proteins · 2026Article
- Variation in the early-life interdigital skin microbiota of lambs in a commercial sheep flock.Frontiers in veterinary science · 2026Article
- Functional and Compositional Changes in Ileal Microbiota in Piglets During the Nursing Period Revealed by 16s rRNA Gene and Metagenomics.Animals : an open access journal from MDPI · 2025Article
- Maternal microbial effects and the dynamic distribution, networks, and functions of pig gut microbiota across the entire life cycle.Scientific reports · 2025Article
- Fecal microbiota transplantation in pigs: current status and future perspective.Animal microbiome · 2025Review
- Composite Probiotics Improve Gut Health and Enhance Tryptophan Metabolism in Nursery Piglets During Liquid Feeding.International journal of molecular sciences · 2025Article
- From mother to piglet: the lasting influence of the maternal microbiome.Animal microbiome · 2025Article
- The impact of pooling on the observed microbiome profile of preweaned piglet feces.FEMS microbiology ecology · 2025Article
- Effects of organic acid-preserved cereal grains in sow diets during late gestation and lactation on the performance and faecal microbiota of sows and their offspring.Journal of animal science and biotechnology · 2025Article
- Feeding Sows with Multi-Species Probiotics During Late Pregnancy and the Lactating Period Influences IgA Concentration in Colostrum and Subsequently Increases the Survival Rate of Piglets in Porcine Epidemic Diarrhea Outbreak Herd.Animals : an open access journal from MDPI · 2025Article
- On-top arginine supplementation during lactation affects milk composition, performance, and intestinal bacterial and viral microbial community of sows and their piglets.Journal of animal science · 2025Article
- MaternalComputational and structural biotechnology journal · 2025Article
- Determinants of piglet gut microbiome colonization: roles of genetics, nutrition, therapeutics, and the impact of enteric pathogens like PEDV.Frontiers in cellular and infection microbiology · 2025Review
- The research progress on the impact of pig gut microbiota on health and production performance.Frontiers in veterinary science · 2025Review
- Bacterial profiles of the oral, vaginal, and rectal mucosa and colostrum of periparturient sows.PloS one · 2025Article
- Maternal Transmission of Rotavirus to Calves and Comparison of Colostrum and Fecal Microbiota in Holstein and Hanwoo Cattle.Veterinary sciences · 2024Article
- The Cellular Microbiome of Visceral Organs: An Inherent Inhabitant of Parenchymal Cells.Microorganisms · 2024Article
- Composition, function, and timing: exploring the early-life gut microbiota in piglets for probiotic interventions.Journal of animal science and biotechnology · 2023Article
- Impact of Early Weaning on Development of the Swine Gut Microbiome.Microorganisms · 2023Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The acquisition and development of the mammalian microbiome early in life are critical to establish a healthy host-microbiome symbiosis. Despite recent advances in understanding microbial sources in infants, the relative contribution of various microbial sources to the colonization of the gut microbiota in pigs remains unclear. Here, we longitudinally sampled the microbiota of 20 sow-piglet pairs (three piglets per sow) reared under identical conditions from multiple body sites and the surrounding weaning environment from birth to 28 days postpartum (1,119 samples in total). Source-tracking analysis revealed that the contribution of various microbial sources to the piglet gut microbiome gradually changed over time. The neonatal microbiota was initially sparsely populated, and the predominant contribution was from the maternal vaginal microbiota that increased gradually from 69.0% at day 0 to 89.3% at day 3 and dropped to 0.28% at day 28. As the piglets aged, the major microbial community patterns were most strongly associated with the sow feces and slatted floor, with contributions increasing from 0.52 and 9.6% at day 0 to 62.1 and 33.8% at day 28, respectively. The intestinal microbial diversity, composition, and function significantly changed as the piglets aged, and 30 age-discriminatory bacterial taxa were identified with distinctive time-dependent shifts in their relative abundance, which likely reflected the effect of the maternal and environmental microbial sources on the selection and adaptation of the piglet gut microbiota. Overall, these data demonstrate that the vaginal microbiota is the primary source of the gut microbiota in piglets within 3 days after birth and are gradually replaced by the sow fecal and slatted floor microbiota over time. These findings may offer novel strategies to promote the establishment of exogenous symbiotic microbes to improve piglet gut health.
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