Evidence map›Paper›PMID 35547149›Full record

ArticleFrontiers in microbiology2022

Longitudinal and Comparative Analysis of Gut Microbiota of Tunisian Newborns According to Delivery Mode.

Mariem Hanachi, Olfa Maghrebi, Haifa Bichiou, Ferdaous Trabelsi, Najla Maha Bouyahia, Fethi Zhioua, Meriam Belghith, Emna Harigua-Souiai, Meriem Baouendi, Lamia Guizani-Tabbane and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Mariem HanachiLaboratory of Bioinformatics, bioMathematics and Biostatistics-LR16IPT09, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Olfa MaghrebiLaboratory of Transmission, Control, and Immunobiology of Infections-LR16 IPT02, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Haifa BichiouLaboratory of Medical Parasitology, Biotechnology, and Biomolecules-LR16 IPT06, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Ferdaous TrabelsiService de Gynécologie et Obstétrique, Hôpital Régional de Zaghouan, Zaghouan, Tunisia.
Najla Maha BouyahiaService de Gynécologie Obstétrique et Médecine de la Reproduction, Hôpital Aziza Othmana, Tunis, Tunisia.
Fethi ZhiouaService de Gynécologie Obstétrique et Médecine de la Reproduction, Hôpital Aziza Othmana, Tunis, Tunisia.
Meriam BelghithLaboratory of Transmission, Control, and Immunobiology of Infections-LR16 IPT02, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Emna Harigua-SouiaiLaboratory of Molecular Epidemiology and Experimental Pathology-LR16IPT04, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Meriem BaouendiLaboratory of Bioinformatics, bioMathematics and Biostatistics-LR16IPT09, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Lamia Guizani-TabbaneLaboratory of Medical Parasitology, Biotechnology, and Biomolecules-LR16 IPT06, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Alia BenkahlaLaboratory of Bioinformatics, bioMathematics and Biostatistics-LR16IPT09, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Oussema SouiaiLaboratory of Bioinformatics, bioMathematics and Biostatistics-LR16IPT09, Institut Pasteur de Tunis, Université de Tunis El Manar, Tunis, Tunisia.
Institut Pasteur de Tunis · TNTunis El Manar University · TNTunis University · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbiota colonization is a dynamic process that impacts the health status during an individual's lifetime. The composition of the gut microbiota of newborns is conditioned by multiple factors, including the delivery mode (DM). Nonetheless, the DM's influence remains uncertain and is still the subject of debate. In this context, the medical indication and the emergency of a cesarean delivery might have led to confounding conclusions regarding the composition and diversity of the neonatal microbiome. Herein, we used high-resolution shotgun sequencing to decipher the composition and dynamics of the gut microbiota composition of Tunisian newborns. Stool samples were collected from 5 elective cesarean section (ECS) and 5 vaginally delivered (VD) newborns at the following time points: Day 0, Day 15, and Day 30. The ECS and VD newborns showed the same level of bacterial richness and diversity. In addition, our data pointed to a shift in microbiota community composition during the first 2 weeks, regardless of the DM. Both ECS and VD showed a profile dominated by Proteobacteria, Actinobacteria, and Firmicutes. However, ECS showed an underrepresentation of

Indexed as

elective cesarean deliveriesESKAPE bacteriamicrobiomenewbornsshotgun metagenome sequencingTunisia

Identifiers

PMID35547149
PMCPMC9083410
OpenAlexW4224861956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.