Evidence map›Paper›PMID 35547075›Full record

ArticleRSC advances2018

NuRD subunit MTA1 interacts with the DNA non-homologous end joining Ku complex in cancer cells.

Jian Liu, Qun Liu, Haijuan Wang, Chunxiao Li, Tao Wen, Guangyu An, Haili Qian

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jian LiuMedical Research Center, Beijing Chao-Yang Hospital, Capital Medical University Beijing 100020 China.ORCID https://orcid.org/0000-0002-8969-8446
Qun LiuDepartment of Obstetrics and Gynecology, Beijing Anzhen Hospital, Capital Medical University Beijing 100029 China.
Haijuan WangState Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100021 China qianhaili001@163.com.
Chunxiao LiState Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100021 China qianhaili001@163.com.
Tao WenMedical Research Center, Beijing Chao-Yang Hospital, Capital Medical University Beijing 100020 China.
Guangyu AnDepartment of Oncology, Beijing Chao-Yang Hospital, Capital Medical University Beijing 100020 China anguangyu@hotmail.com.
Haili QianState Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100021 China qianhaili001@163.com.
Capital University · USChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastasis-associated antigen 1 (MTA1) is a chromatin modifier mediating DNA modification and gene expression. Ku70/Ku80 complex has been reported to be essential in DNA damage response. In an effort to explore the MTA1 interactome, we captured the Ku70/Ku80 complex with two specific MTA1 antibodies in a colon cancer cell line. We first validated the

Identifiers

PMID35547075
PMCPMC9087872
OpenAlexW2896806109

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.