Evidence map›Paper›PMID 35547072›Full record

ArticleRSC advances2018

Retracted Article: MiR-182-5p and miR-96-5p increased hepatocellular carcinoma cell mobility, proliferation and cisplatin resistance partially by targeting RND3.

Shiming Yang, Zhi Chen, Daguang Fan, Rui Zhang, Yuhong Zhang, Shusheng Wu

RetractedAbstract readRetracted Publication
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Shiming YangDepartment of General Surgery, Shanxi Provincial People's Hospital No. 29, Shuangtaisi Street Taiyuan Shanxi 030012 China ysm529@126.com +86-0351-4960336.
Zhi ChenDepartment of General Surgery, Shanxi Provincial People's Hospital No. 29, Shuangtaisi Street Taiyuan Shanxi 030012 China ysm529@126.com +86-0351-4960336.
Daguang FanDepartment of General Surgery, Shanxi Provincial People's Hospital No. 29, Shuangtaisi Street Taiyuan Shanxi 030012 China ysm529@126.com +86-0351-4960336.
Rui ZhangDepartment of General Surgery, Shanxi Provincial People's Hospital No. 29, Shuangtaisi Street Taiyuan Shanxi 030012 China ysm529@126.com +86-0351-4960336.
Yuhong ZhangDepartment of General Surgery, Shanxi Provincial People's Hospital No. 29, Shuangtaisi Street Taiyuan Shanxi 030012 China ysm529@126.com +86-0351-4960336.
Shusheng WuDepartment of General Surgery, Shanxi Provincial People's Hospital No. 29, Shuangtaisi Street Taiyuan Shanxi 030012 China ysm529@126.com +86-0351-4960336.ORCID 0000-0001-7626-1811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated whether miR-182-5p or miR-96-5p could increase hepatocellular carcinoma (HCC) development by targeting Rho Family GTPase 3 (RND3) gene expression. The expression levels of miR-182-5p, miR-96-5p and mRNA/protein of RND3 in non-HCC liver tissue, HCC tissue and adjacent tissue specimens were evaluated by RT-qPCR and western blot. Patient-derived HCC cell culture was established, and miR-182-5p or miR-96-5p agomir or antagomir treatment was performed to mimic the overexpression or knockdown of the two miRNAs. HCC cell mobility

Identifiers

PMID35547072
PMCPMC9087357

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.