Evidence map›Paper›PMID 35546974›Full record

ArticleArchives of Razi Institute2021

Effect of Honey Bee Venom on Experimental Autoimmune Encephalomyelitis (EAE) as a Model for Multiple Sclerosis (MS).

Sh Jelodar, A Zare Mirakabadi, Sh Oryan, L Mohammadnejad

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of Razi Institute, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sh JelodarDepartment of Biology, Islamic Azad University, Science and Research Branch, Tehran, Iran.
A Zare MirakabadiDepartment of Venomous Animals and Anti Venom Production, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.
Sh OryanDepartment of Biology, Kharazmi University, Tehran, Iran.
L MohammadnejadBiology, Basic Sciences, Azad Islamic University, Sciences and Research Branch, Tehran, Iran.
Islamic Azad University, Science and Research Branch · IRKharazmi University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experimental autoimmune encephalomyelitis (EAE) has been widely employed as a model to study multiple sclerosis (MS). Interleukin-27 (IL-27) inhibits Th17 activity and breaks the normal activity of effector T cells which cause autoimmunity. Bee venom (BV) has been used as a form of medicine from the time of ancient Greece and China. BV and BV-derived active components might have potent therapeutic effects on refractory immunological and neurodegenerative diseases, such as MS. This study aimed to investigate the effect of Iranian honey bee venom on the progression of EAE in mice. Initially, EAE was induced in 12 female C57BL/6 mice through immunization with an emulsion of myelin oligodendrocyte glycoprotein 35-55 (MOG

Indexed as

Bee VenomsEncephalomyelitis, Autoimmune, ExperimentalInterleukin-27Multiple SclerosisAnimalsFemaleIranMiceMice, Inbred C57BLPeptide FragmentsBee VenomsInterleukin-27Peptide FragmentsBee venomC57BL/6 miceExperimental autoimmune encephalomyelitisInterleukin-27MOGMultiple sclerosis

Identifiers

PMID35546974
PMCPMC9083859
OpenAlexW3131306013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.