Evidence map›Paper›PMID 35546825›Full record

ArticleRSC advances2018

Study of oxygen tension variation within live tumor spheroids using microfluidic devices and multi-photon laser scanning microscopy.

Sreerupa Sarkar, Chien-Chung Peng, Chiung Wen Kuo, Di-Yen Chueh, Hsiao-Mei Wu, Yuan-Hsuan Liu, Peilin Chen, Yi-Chung Tung

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Beyond monolayers: a comparative analysis of 2D cell cultures and 3DFrontiers in bioengineering and biotechnology · 2026
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  9. Fabrication of PNIPAm-based thermoresponsive hydrogel microwell arrays for tumor spheroid formation.Materials science & engineering. C, Materials for biological applications · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sreerupa SarkarDepartment of Engineering and System Science, National Tsing Hua University Hsinchu 30013 Taiwan.
Chien-Chung PengResearch Center for Applied Sciences, Academia Sinica Taipei 11529 Taiwan tungy@gate.sinica.edu.tw.
Chiung Wen KuoResearch Center for Applied Sciences, Academia Sinica Taipei 11529 Taiwan tungy@gate.sinica.edu.tw.
Di-Yen ChuehResearch Center for Applied Sciences, Academia Sinica Taipei 11529 Taiwan tungy@gate.sinica.edu.tw.
Hsiao-Mei WuResearch Center for Applied Sciences, Academia Sinica Taipei 11529 Taiwan tungy@gate.sinica.edu.tw.
Yuan-Hsuan LiuResearch Center for Applied Sciences, Academia Sinica Taipei 11529 Taiwan tungy@gate.sinica.edu.tw.
Peilin ChenResearch Center for Applied Sciences, Academia Sinica Taipei 11529 Taiwan tungy@gate.sinica.edu.tw.
Yi-Chung TungResearch Center for Applied Sciences, Academia Sinica Taipei 11529 Taiwan tungy@gate.sinica.edu.tw.ORCID https://orcid.org/0000-0002-6170-2992
Research Center for Applied Science, Academia Sinica · TWChang Gung University · TWNational Tsing Hua University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional cell spheroid culture using microfluidic devices provides a convenient

Identifiers

PMID35546825
PMCPMC9085395
OpenAlexW2889488657

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.