ArticleBMC endocrine disorders2022
Impact of anxiety, depression and disease-related distress on long-term glycaemic variability among subjects with Type 1 diabetes mellitus.
Article in BMC endocrine disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Psychosocial outcomes among adults with type 1 diabetes using a tubeless automated insulin delivery system compared with sensor augmented pump therapy: A randomised, parallel-group clinical trial sub-study.Diabetes, obesity & metabolism · 2026Trial
- Evaluating the Specific Role of Dysfunctional Metacognitive Beliefs and Testing a Metacognitive Model of Emotional Distress in Patients with Type 1 Diabetes Mellitus.Journal of clinical psychology in medical settings · 2026Article
- Psychological distress and its influence on medication adherence among patients with co-morbid hypertension and diabetes: an explanatory sequential mixed-methods study.BMC public health · 2026Article
- Living with what is lost: reframing emotional life with diabetes through an integrative perspective on loss and grief.Frontiers in clinical diabetes and healthcare · 2026Article
- Type 1 Diabetes Mellitus and Alexithymia: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Association between cerebral lesions and the severity of diabetic cardiovascular disease, retinopathy, and nephropathy-new lessons to learn from neuroimaging.Journal of endocrinological investigation · 2025Review
- Proposed Practical Guidelines to Improve Glycaemic Management by Reducing Glycaemic Variability in People with Type 1 Diabetes Mellitus.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Review
- Impact of family environment on mental disorders and quality of life in children with type 1 diabetes mellitus: a cross-sectional study and intervention policy analysis.Frontiers in pediatrics · 2025Article
- Sex-driven factors associated with anxiety and depression in autoimmune diabetes.Acta diabetologica · 2024Article
- Moderating effect for illness uncertainty on the relationship of depressive and anxiety symptoms among patients with type 1 diabetes in Taif region, Saudi Arabia.Journal of family medicine and primary care · 2024Article
- Diabetes Stigma and Psychosocial Outcomes in Adolescents and Young Adults: The SEARCH for Diabetes in Youth Study.Diabetes care · 2024Article
- Association of Physical Activity and Sleep Metrics with Depression in People with Type 1 Diabetes.Psychology research and behavior management · 2024Article
- The Interaction of Glycemia with Anxiety and Depression Is Related to Altered Cerebellar and Cerebral Functional Correlations.Brain sciences · 2023Article
- Comparison of diabetes distress and depression screening results of emerging adults with type 1 diabetes onset at different ages: findings from the German early-onset T1D study and the German Diabetes Study (GDS).Diabetology & metabolic syndrome · 2023Article
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6 authors.
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Abstract
backgroundAnxiety, depression, and disease-related distress are linked to worse overall glycaemic control, in terms of HbA1c. This study was aimed to evaluate whether traits of these emotional disorders are associated with long-term glycaemic variability in subjects with Type 1 diabetes.
methodsLongitudinal retrospective study. Six-year HbA1c data (2014-2019) from 411 subjects with Type 1 diabetes who had participated in a previous study to design a diabetes-specific quality of life questionnaire in the year 2014 were included. Scores for Spanish versions of the Hospital Anxiety and Depression Scale (HADS) and Problem Areas in Diabetes (PAID) scale were obtained at baseline, along with sociodemographic and clinical data. Long-term glycaemic variability was measured as the coefficient of variation of HbA1c (HbA1c-CV). The association between HADS and PAID scores and HbA1c-CV was analysed with Spearman correlations and multiple regression models, both linear and additive, including other covariates (age, sex, diabetes duration time, type of treatment, baseline HbA1c, use of anxiolytic or antidepressant drugs, education level and employment status).
resultsScores of depression, anxiety and distress were positively and significantly correlated to HbA1c-CV in univariate analyses. Multiple regression study demonstrated an independent association only for diabetes distress score (p < 0.001). Age, diabetes duration time, baseline HbA1c, education level and employment status were also significantly associated with HbA1c-CV. However, when subjects were analyzed separately in two age groups, distress scores were associated with HbA1c-CV only among those aged 25 years or older, while anxiety scores, but not distress, were associated with HbA1c-CV among those younger than 25 years.
conclusionsPsychological factors, particularly disease-related distress and anxiety, are associated with long-term glycaemic variability in subjects with Type 1 diabetes.
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