Evidence map›Paper›PMID 35546597›Full record

ArticleScientific reports2022

A statistical shape model of soleus muscle morphology in spastic cerebral palsy.

Salim G Bin Ghouth, Sian A Williams, Siobhan L Reid, Thor F Besier, Geoffrey G Handsfield

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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  9. Morphological variations in the talus and calcaneus in adults with cerebral palsy comparing with and without lateral column lengthening.The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Salim G Bin GhouthAuckland Bioengineering Institute, University of Auckland, Auckland, 1010, New Zealand.
Sian A WilliamsCurtin School of Allied Health, Curtin University, Perth, WA, 6845, Australia.
Siobhan L ReidSchool of Human Sciences (Exercise Science), University of Western Australia, Perth, WA, 6009, Australia.
Thor F BesierAuckland Bioengineering Institute, University of Auckland, Auckland, 1010, New Zealand.
Geoffrey G HandsfieldAuckland Bioengineering Institute, University of Auckland, Auckland, 1010, New Zealand. g.handsfield@auckland.ac.nz.
University of Auckland · NZCurtin University · AUUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated morphological characteristics of the soleus muscle in cerebral palsy (CP) and typically developing (TD) cohorts using a statistical shape model and differentiated dominant features between the two cohorts. We generated shape models of CP and TD cohorts to characterize dominant features within each. We then generated a combined shape model of both CP and TD to assess deviations of the cohorts' soleuses from a common mean shape, and statistically analysed differences between the cohorts. The shape models revealed similar principal components (PCs) with different variance between groups. The CP shape model yielded a distinct feature (superior-inferior shift of the broad central region) accounting for 8.1% of the model's cumulative variance. The combined shape model presented two PCs where differences arose between CP and TD cohorts: size and aspect ratio of length-width-thickness. The distinct appearance characteristic in the CP model-described above-may implicate impaired muscle function in children with CP. Overall, children with CP had smaller muscles that also tended to be long, thin, and narrow. Shape modelling captures dominant morphological features of structures, which was used here to quantitatively describe CP muscles and further probe our understanding of the disease's impact on the muscular system.

Indexed as

Cerebral PalsyChildHumansModels, StatisticalMuscle, Skeletal

Identifiers

PMID35546597
PMCPMC9095689
OpenAlexW4280574765

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.