Evidence map›Paper›PMID 35546552›Full record

ArticleNature communications2022

Immunoprofiling reveals cell subsets associated with the trajectory of cytomegalovirus reactivation post stem cell transplantation.

Lauren Stern, Helen M McGuire, Selmir Avdic, Barbara Fazekas de St Groth, David Gottlieb, Allison Abendroth, Emily Blyth, Barry Slobedman

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Adoptive T-cell therapy for virus-associated diseases.Clinical microbiology reviews · 2025
    Review
  4. The immune response to human cytomegalovirus: impact of age, co-morbidities and the significance of anti-viral activity assessment.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The Emerging Role of MAIT Cell Responses in Viral Infections.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lauren SternSchool of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.ORCID 0000-0002-9455-0008
Helen M McGuireSchool of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
Selmir AvdicWestmead Institute for Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
Barbara Fazekas de St GrothSchool of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.ORCID 0000-0001-6817-9690
David GottliebWestmead Institute for Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
Allison AbendrothSchool of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
Emily BlythWestmead Institute for Medical Research, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.ORCID 0000-0002-7849-7139
Barry SlobedmanSchool of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia. barry.slobedman@sydney.edu.au.ORCID 0000-0002-9431-6094
The University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human cytomegalovirus reactivation is a major opportunistic infection after allogeneic haematopoietic stem cell transplantation and has a complex relationship with post-transplant immune reconstitution. Here, we use mass cytometry to define patterns of innate and adaptive immune cell reconstitution at key phases of human cytomegalovirus reactivation in the first 100 days post haematopoietic stem cell transplantation. Human cytomegalovirus reactivation is associated with the development of activated, memory T-cell profiles, with faster effector-memory CD4

Indexed as

Cytomegalovirus InfectionsHematopoietic Stem Cell TransplantationCytomegalovirusHumans

Identifiers

PMID35546552
PMCPMC9095831
OpenAlexW4280562836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.