Evidence map›Paper›PMID 35546368›Full record

ArticleJournal of molecular modeling2022

Indole alkaloids as potential candidates against COVID-19: an in silico study.

Mehran Mohseni, Hamed Bahrami, Bahman Farajmand, Faezeh Sadat Hosseini, Massoud Amanlou, Hafezeh Salehabadi

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular modeling, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mehran MohseniDepartment of Food and Drug Control, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.
Hamed BahramiDepartment of Chemistry, Faculty of Science, University of Zanjan, Zanjan, Iran.
Bahman FarajmandDepartment of Chemistry, Faculty of Science, University of Zanjan, Zanjan, Iran.
Faezeh Sadat HosseiniDepartment of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Massoud AmanlouDepartment of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Hafezeh SalehabadiDepartment of Medicinal Chemistry, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran. hsalehabadi@zums.ac.ir.ORCID http://orcid.org/0000-0001-5014-2216
Tehran University of Medical Sciences · IRUniversity of Zanjan · IRZanjan University of Medical Sciences · IR

Funding

Zanjan University of Medical Sciences A-11-1510-1
6 · The paper itself

Abstract

COVID-19 has recently grown to be pandemic all around the world. Therefore, efforts to find effective drugs for the treatment of COVID-19 are needed to improve humans' life quality and survival. Since the main protease (M

Indexed as

AlkaloidsCOVID-19 Drug TreatmentAntiviral AgentsHumansIndole AlkaloidsMolecular Docking SimulationMolecular Dynamics SimulationProtease InhibitorsSARS-CoV-2AlkaloidsAntiviral AgentsIndole AlkaloidsProtease InhibitorsDockingIndole alkaloidsMM-PBSAMolecular dynamic simulationsSARS-CoV-2 main protease inhibitorVirtual screening

Identifiers

PMID35546368
PMCPMC9094126
OpenAlexW4280608228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.