Evidence map›Paper›PMID 35546294›Full record

ArticleMycoses2022

Emergence of Candida auris in intensive care units in Algeria.

Hanane Zerrouki, Ahmad Ibrahim, Sid-Ahmed Rebiahi, Yamina Elhabiri, Djamel-Eddine Benhaddouche, Theun de Groot, Jacques F Meis, Jean-Marc Rolain, Fadi Bittar

Open access · hybridAbstract read
In one paragraph

Article in Mycoses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Journal of fungi (Basel, Switzerland) · 2026
    Review
  3. A Cross-Sectional Study to DetermineBioMed research international · 2026
    Article
  4. Diagnostic Approaches forMicroorganisms · 2025
    Review
  5. Article
  6. Open forum infectious diseases · 2024
    Review
  7. Potential Environmental Reservoirs ofJournal of fungi (Basel, Switzerland) · 2024
    Review
  8. Current global status of Candida auris an emerging multidrug-resistant fungal pathogen: bibliometric analysis and network visualization.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  9. Article
  10. Emergence ofSAGE open medical case reports · 2024
    Article
  11. An Autochthonous SusceptibleJournal of fungi (Basel, Switzerland) · 2023
    Article
  12. Increasing Number of Cases Due toJournal of clinical medicine · 2023
    Article
  13. Fast and Accurate Identification ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  14. Article
  15. Emergence and Genomic Characterization of Multidrug ResistantJournal of fungi (Basel, Switzerland) · 2022
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Hanane ZerroukiAix-Marseille Université, IRD, APHM, MEPHI, Marseille, France.
Ahmad IbrahimAix-Marseille Université, IRD, APHM, MEPHI, Marseille, France.
Sid-Ahmed RebiahiLaboratoire de Microbiologie Appliquée à l'Agroalimentaire, au Biomédical et à l'Environnement, Université de Tlemcen, Tlemcen, Algeria.
Yamina ElhabiriLaboratoire de Microbiologie Appliquée à l'Agroalimentaire, au Biomédical et à l'Environnement, Université de Tlemcen, Tlemcen, Algeria.
Djamel-Eddine BenhaddoucheService d'anesthésie et de réanimation, Centre Hospitalo-Universitaire Tlemcen, Tlemcen, Algeria.
Theun de GrootDepartment of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Jacques F MeisDepartment of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Jean-Marc RolainAix-Marseille Université, IRD, APHM, MEPHI, Marseille, France.
Fadi BittarAix-Marseille Université, IRD, APHM, MEPHI, Marseille, France.ORCID https://orcid.org/0000-0003-4052-344X
Aix-Marseille Université · FRUniversity of Abou Bekr Belkaïd · DZRadboud University Nijmegen · NL

Funding

Agence Nationale de la Recherche
6 · The paper itself

Abstract

backgroundCurrently, Candida auris is among the most serious emerging pathogens that can be associated with nosocomial infections and outbreaks in intensive care units. Clinicians must be able to identify and manage it quickly.

objectiveHere, we report for the first time in Algeria seven cases of C. auris infection or colonisation. METHODS AND

resultsThe strains were isolated from clinical sites including bronchial aspirates (n = 4), wound swabs (n = 1), urine sample (n = 1) and peritoneal fluid (n = 1), in patients admitted to the intensive care unit. Candida auris was identified both by MALDI-TOF and by sequencing the ITS region and the D1/D2 domain. Antifungal susceptibility testing was performed using the E-test method. Non-wildtype susceptibility was observed for five strains against fluconazole, itraconazole, voriconazole and caspofungin. Genotyping showed the presence of four clades (I-IV) in one hospital.

conclusionsAppropriate antifungal treatments with rapid and accurate microbial identification are the cornerstone for the management and control of C. auris infections.

Indexed as

Antifungal AgentsCandidiasisAlgeriaCandidaCandida aurisHumansIntensive Care UnitsMicrobial Sensitivity TestsAntifungal AgentsAlgeriaCandida aurisclades (I-IV)emergenceICU

Identifiers

PMID35546294
PMCPMC9328195
OpenAlexW4280505676

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.