Evidence map›Paper›PMID 35546203›Full record

ArticleEuropean biophysics journal : EBJ2022

Amyloid fibril length distribution from dynamic light scattering data.

Petr A Sokolov, Valeriy I Rolich, Olga S Vezo, Mikhail V Belousov, Stanislav A Bondarev, Galina A Zhouravleva, Nina A Kasyanenko

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Article in European biophysics journal : EBJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Petr A SokolovDepartment of Physics, St. Petersburg University, 7-9-11 Universitetskaya Emb, St. Petersburg, 199034, Russia. p.a.sokolov@spbu.ru.ORCID http://orcid.org/0000-0003-4819-3211
Valeriy I RolichDepartment of Physics, St. Petersburg University, 7-9-11 Universitetskaya Emb, St. Petersburg, 199034, Russia.
Olga S VezoDepartment of Physics, St. Petersburg University, 7-9-11 Universitetskaya Emb, St. Petersburg, 199034, Russia.
Mikhail V BelousovDepartment of Genetics and Biotechnology, St. Petersburg University, 7-9-11 Universitetskaya Emb, St. Petersburg, 199034, Russia.
Stanislav A BondarevDepartment of Genetics and Biotechnology, St. Petersburg University, 7-9-11 Universitetskaya Emb, St. Petersburg, 199034, Russia.
Galina A ZhouravlevaDepartment of Genetics and Biotechnology, St. Petersburg University, 7-9-11 Universitetskaya Emb, St. Petersburg, 199034, Russia.
Nina A KasyanenkoDepartment of Physics, St. Petersburg University, 7-9-11 Universitetskaya Emb, St. Petersburg, 199034, Russia.

Funding

Russian Science Foundation 22-25-00302Russian Science Foundation 22-26-00276
6 · The paper itself

Abstract

The study of the aggregation of amyloid proteins is challenging. A new approach to processing dynamic light scattering data was developed and tested using aggregates of the well-known model Sup35NM amyloid. After filtering and calculating the moving averages of autocorrelation functions to reduce impacts of noise, each averaged autocorrelation function is converted to the fibril length distribution via numerical modeling. The processing results were verified using atomic force and scanning electron microscopy data. Analysis of fibril length distribution changes over time gives valuable information about the aggregation process.

Indexed as

AmyloidAmyloid beta-PeptidesDynamic Light ScatteringMicroscopy, Atomic ForceAmyloidAmyloid beta-PeptidesAmyloidDLSEPJE-D-21–00,098Number distributionPrionSEM

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.