ArticleScientific reports2022
COVID-19 infections in infants.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 27 citations in OpenAlex.
- SARS-CoV-2 in Infants: Clinical Patterns, Laboratory Findings, and Implications for Pediatric Care in Viral Outbreaks.Clinical medicine insights. Pediatrics · 2026Article
- SARS-CoV-2-International journal of microbiology · 2026Review
- Anxiety in mothers of children with COVID-19 based on the State-Trait Anxiety Inventory.Revista brasileira de enfermagem · 2026Article
- Coronavirus research topics, tracking twenty years of research.Scientific data · 2025Article
- Post-COVID-19 Neutropenia in an Infant With Thalassemia Minor: Case Report.Clinical case reports · 2025Article
- Retrospective longitudinal study on the long-term impact of COVID-19 infection on polysomnographic evaluation in patients with Prader-Willi syndrome.Orphanet journal of rare diseases · 2024Article
- Clinical Outcomes and Characteristics of COVID-19 in Neonates: A Single-Center Study in Romania.Life (Basel, Switzerland) · 2024Article
- Article
- Stratifying Disease Severity in Pediatric COVID-19: A Correlative Study of Serum Biomarkers and Lung Ultrasound-A Retrospective Observational Dual-Center Study.Diagnostics (Basel, Switzerland) · 2024Article
- Clinical Differences between SARS-CoV-2 and RSV Infections in Infants: Findings from a Case-Control Study.Viruses · 2023Article
- Comparative Analysis of Symptomatology in Hospitalized Children with RSV, COVID-19, and Influenza Infections.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Incidental Hyperferritinemia in Very Young Infants with Mild Symptoms of COVID-19 Disease.Children (Basel, Switzerland) · 2023Article
- The Immunological Profile of SARS-CoV-2 Infection in Children Is Linked to Clinical Severity and Age.International journal of molecular sciences · 2023Article
- Clinical Course and Severity of COVID-19 in 940 Infants with and without Comorbidities Hospitalized in 2020 and 2021: The Results of the National Multicenter Database SARSTer-PED.Journal of clinical medicine · 2023Article
- COVID-19 Disease in Under-5 Children: Current Status and Strategies for Prevention including Vaccination.Vaccines · 2023Review
- SARS-CoV-2 seroprevalence in children worldwide: A systematic review and meta-analysis.EClinicalMedicine · 2023Article
- Omicron in Infants-Respiratory or Digestive Disease?Diagnostics (Basel, Switzerland) · 2023Article
- Causes of Intensive Care Unit Admissions in Children with SARS-CoV-2: A Single-Centre Observational Study.Children (Basel, Switzerland) · 2022Article
- The Age-Related Course of COVID-19 in Pediatric Patients-1405 Cases in a Single Center.Journal of clinical medicine · 2022Article
- The Seroprevalence of SARS-CoV-2 IgG Antibodies in Children Hospitalized for Reasons Other Than COVID-19.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
28 authors at 11 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study aimed to analyse the clinical course of COVID-19 in 300 infants, selected from 1283 children diagnosed with COVID-19 between March and December 2020, registered in the SARSTerPED multicenter database. Most of the infants were registered in October and November 2020. 44% of the group were girls, and 56% were boys. At diagnosis, the most common symptoms were fever in 77% of the children, cough in 40%, catarrh in 37%. Pneumonia associated with COVID-19 was diagnosed in 23% of the children, and gastrointestinal symptoms in 31.3%. In 52% of the infants, elevated levels of D-dimers were observed, and in 40%, elevated levels of IL-6 serum concentration were observed. During the second wave of the pandemic, 6 times more infants were hospitalized, and the children were statistically significantly younger compared to the patients during the first wave (3 months vs 8 months, p < 0.0001 respectively). During the second wave, the infants were hospitalized for longer. COVID-19 in infants usually manifests as a mild gastrointestinal or respiratory infection, but pneumonia is also observed with falls in oxygen saturation, requiring oxygen therapy. Gastrointestinal symptoms are common in infants infected with SARS-CoV-2, and infant appetite disorders may lead to hospitalization. The clinical course of the disease differed significantly between the first and second wave of the pandemic. It seems that infants may play a role in the transmission of SARS-COV-2 infections in households, despite mild or asymptomatic courses; eating disorders in infants should be an indication for COVID-19 testing.
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