Evidence map›Paper›PMID 35546120›Full record

ArticleJournal of virology2022

Pathobiology of an NS1-Truncated H3N2 Swine Influenza Virus Strain in Pigs.

Elien Vandoorn, Wojciech Stadejek, Anna Parys, Sharon Chepkwony, Koen Chiers, Kristien Van Reeth

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elien VandoornLaboratory of Virology, Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Merelbeke, Belgium.ORCID 0000-0003-0037-2675
Wojciech StadejekLaboratory of Virology, Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Merelbeke, Belgium.
Anna ParysLaboratory of Virology, Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Merelbeke, Belgium.
Sharon ChepkwonyLaboratory of Virology, Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Merelbeke, Belgium.
Koen ChiersLaboratory of Veterinary Pathology, Department of Pathobiology, Pharmacology and Zoological Medicine, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Merelbeke, Belgium.
Kristien Van ReethLaboratory of Virology, Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Merelbeke, Belgium.
Ghent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virus strains in the live attenuated influenza vaccine (LAIV) for swine in the United States that was on the market until 2020 encode a truncated nonstructural protein 1 of 126 amino acids (NS1del126). Their attenuation is believed to be due to an impaired ability to counteract the type I interferon (IFN)-mediated antiviral host response. However, this mechanism has been documented only

Indexed as

Influenza A Virus, H3N2 SubtypeInfluenza VaccinesOrthomyxoviridae InfectionsSwine DiseasesAnimalsInterferon Type ISwineVaccines, AttenuatedViral Nonstructural ProteinsInfluenza VaccinesINS1 protein, influenza virusInterferon Type IVaccines, AttenuatedViral Nonstructural ProteinsattenuationH3N2influenza ANS1pathobiologyswinetype I interferon

Identifiers

PMID35546120
PMCPMC9175629
OpenAlexW4280610413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.