Evidence map›Paper›PMID 35546119›Full record

ArticleJournal of virology2022

Rb-E2F-HDAC Repressor Complexes Control Interferon-Induced Repression of Adenovirus To Promote Persistent Infection.

Sydney Snaider, Yueting Zheng, Patrick Hearing

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sydney SnaiderDepartment of Microbiology and Immunology, Renaissance School of Medicine, Stony Brook Universitygrid.36425.36, Stony Brook, New York, USA.
Yueting ZhengSynthego Corporation, Menlo Park, California, USA.
Patrick HearingDepartment of Microbiology and Immunology, Renaissance School of Medicine, Stony Brook Universitygrid.36425.36, Stony Brook, New York, USA.ORCID 0000-0003-0400-1660
Stony Brook School · USMenlo School · US

Funding

Regulation of Nuclear Signaling Pathways by the Adenovirus E4-ORF3 ProteinR01CA122677 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI HEARING, PATRICK · 2007 to 2022
$5.2M
MOLECULAR AND CELL BIOLOGY OF INFECTIOUS DISEASEST32AI007539 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI KONOPKA, JAMES B · 1998 to 2023
$3.6M
HHS | National Institutes of Health (NIH) R01CA122677HHS | National Institutes of Health (NIH) T32AI007539NCI NIH HHS R01 CA122677NIAID NIH HHS T32 AI007539
6 · The paper itself

Abstract

Interferons (IFNs) are cytokines that induce a global change in the cell to establish antiviral immunity. We previously demonstrated that human adenovirus (HAdV) exploits IFN-induced viral repression to persist in infected cells. Although this

Indexed as

Adenoviruses, HumanAdenovirus Infections, HumanInterferonsPersistent InfectionE2F Transcription FactorsHistone DeacetylasesHumansRetinoblastoma ProteinE2F Transcription FactorsHistone DeacetylasesInterferonsRetinoblastoma Proteinadenovirusinterferonpersistent infectionretinoblastoma protein

Identifiers

PMID35546119
PMCPMC9175624
OpenAlexW4280501426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.