Trial reportActa bio-medica : Atenei Parmensis2022
The Listening to music tuned to 440 Hz versus 432 Hz to reduce anxiety and stress in emergency nurses during the COVID-19 pandemic: a double-blind, randomized controlled pilot study.
Trial report in Acta bio-medica : Atenei Parmensis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06349200 (Comparing Binaural Beats and 432Hz Music for Reduction of Preoperative Anxiety in Root Canal Patients), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparing Binaural Beats and 432Hz Music for Reduction of Preoperative Anxiety in Root Canal Patients: an RCT Study
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Supporting emergency departments workers well-being: a systematic review of the literature on interventions.Internal and emergency medicine · 2026Pooled it
- Acute Music-Frequency Exposure Modulates Salivary Stress and Neurotrophic Markers in Young Adults: A Randomized Controlled Trial.Brain and behavior · 2026Trial
- Differential effects of sound interventions tuned to 432 Hz or 443 Hz on cardiovascular parameters in cancer patients: a randomized cross-over trial.BMC complementary medicine and therapies · 2025Trial
- Music Listening in Medicine and Healthcare: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Music-based interventions at workplaces: a scoping review.BMC complementary medicine and therapies · 2025Article
- Effects of Sound Interventions on the Mental Stress Response in Adults: Scoping Review.JMIR mental health · 2025Article
- Managing the work stress of inpatient nurses during the COVID-19 pandemic: a systematic review of organizational interventions.BMC nursing · 2024Article
- Arts therapies for mental disorders in COVID-19 patients: a comprehensive review.Frontiers in public health · 2023Review
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimHealthcare providers in the emergency first response units have been exposed to a considerable stress during the SARS-CoV-2 pandemic. This study was designed to identify the effects of listening to music during the work break compared to the routine break (in the absence of listening to music) on the level of state anxiety and on the vital parameters of the nurses on duty at the operations center.
methodsRandomized, controlled, three-arm, double-blind, single-center clinical study. Healthcare providers were divided into three groups according to study intervention (Group 1: listening to 440Hz music; Group 2: listening to 432Hz music; Group 3: liberal activity). The study was conducted during the working hours of dayshifts in an emergency first response unit station located in Tuscany, Italy. Outcomes were measured against measures of stress (State-Trait Anxiety Inventory - STAIX1), heart rate (HR), respiratory rate (RR), systolic/diastolic blood pressure (SBP/DBP), pain and productivity (Likert Scale) measured at baseline (T0) and at the end of exposure (T1).
resultsOverall, 54 healthcare providers were enrolled; 32 females (59.3%); mean age of 39.64 years (SD±9.94); the total measurements performed were 83. The median values of STAI X1 decreased in all the 3 groups from T0 to T1 (Group 1: 34.5 vs. 32, p=0.0001; Group 2: 34 vs. 29, p=0.001; Group 3: 33 vs. 31, p=0.028). In Group 2 a reduction of mean values of respiratory rate and systolic blood pressure was recorded at T1 (-2.714 b/min, p=0.000 and -3.821 mmHg, p=0.031, respectively).
conclusionsListening to music at 432 Hz is a low cost and short intervention that can be a useful resource to manage anxiety and stress. Further studies are needed to assess medium and long-term effects of listening to music.
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