Evidence map›Paper›PMID 35545836›Full record

SynthesisEpilepsia2022

Automated seizure detection with noninvasive wearable devices: A systematic review and meta-analysis.

Vaidehi Naganur, Shobi Sivathamboo, Zhibin Chen, Shitanshu Kusmakar, Ana Antonic-Baker, Terence J O'Brien, Patrick Kwan

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Epilepsia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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  16. Near SUDEP in a patient with craniosynostosis syndrome and temporal lobe encephaloceles.Epileptic disorders : international epilepsy journal with videotape · 2025
    Article
  17. Seizure Detection Devices.Journal of clinical medicine · 2025
    Review
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Vaidehi NaganurDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-3651-6071
Shobi SivathambooDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Zhibin ChenDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Shitanshu KusmakarDepartment of Electrical and Electronic Engineering, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-6689-9405
Ana Antonic-BakerDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Terence J O'BrienDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Patrick KwanDepartment of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0001-7310-276X
The Royal Melbourne Hospital · AUMonash University · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was undertaken to review the reported performance of noninvasive wearable devices in detecting epileptic seizures and psychogenic nonepileptic seizures (PNES).

methodsWe conducted a systematic review and meta-analysis of studies reported up to November 15, 2021. We included studies that used video-electroencephalographic (EEG) monitoring as the gold standard to determine the sensitivity and false alarm rate (FAR) of noninvasive wearables for automated seizure detection.

resultsTwenty-eight studies met the criteria for the systematic review, of which 23 were eligible for meta-analysis. These studies (1269 patients in total, median recording time = 52.9 h per patient) investigated devices for tonic-clonic seizures using wrist-worn and/or ankle-worn devices to measure three-dimensional accelerometry (15 studies), and/or wearable surface devices to measure electromyography (eight studies). The mean sensitivity for detecting tonic-clonic seizures was .91 (95% confidence interval [CI] = .85-.96, I SIGNIFICANCE: Reported noninvasive wearable devices had high sensitivity but relatively high FARs in detecting tonic-clonic seizures during limited recording time in a video-EEG setting. Future studies should focus on reducing FAR, detection of other seizure types and PNES, and longer recording in the community.

Indexed as

EpilepsyWearable Electronic DevicesAccelerometryElectroencephalographyHumansPsychogenic Nonepileptic SeizuresSeizuresambulatory/noninvasive deviceautomated seizure detectionepilepsy/seizuresvideo/EEG use in epilepsy

Identifiers

PMID35545836
PMCPMC9545631
OpenAlexW4280516165

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.