ArticleJournal of cardiothoracic surgery2022
Quality of life and frailty outcomes following surgical and transcatheter aortic valve replacement.
Article in Journal of cardiothoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Prevalence and course of depression in older people with aortic stenosis undergoing transcatheter aortic valve implantation - a systematic review and meta-analysis.BMC geriatrics · 2025Pooled it
- Rebuilding life after heart valve surgery: The VALCAR(E)_QoL study on rehabilitation and quality of life.MethodsX · 2026Article
- Trajectory of cognitive function and quality of life following stenotic aortic valve procedures.Frontiers in cardiovascular medicine · 2026Article
- The effects of frailty, mental health, and cardiac function on quality of life in patients undergoing transcatheter aortic valve replacement.Scientific reports · 2025Article
- Frailty and cardiovascular disease: a bidirectional relationship with clinical implications.Frontiers in cardiovascular medicine · 2025Review
- Surgical and transcatheter aortic valve replacement align survival with general population expectations: insights from standardized mortality ratios.Frontiers in cardiovascular medicine · 2025Article
- Quality of life and functional capacity in patients after cardiac surgery intensive care unit.World journal of cardiology · 2024Review
- Frailty and Cardiovascular Health.Journal of the American Heart Association · 2024Review
- Sarcopenia and aortic valve disease.Heart (British Cardiac Society) · 2024Review
- Review
- Demystifying the Value of Minimal Clinically Important Difference in the Cardiothoracic Surgery Context.Life (Basel, Switzerland) · 2023Review
- SurgicalPeerJ · 2023Observational
- Review
- Mental health and transcatheter aortic valve replacement: A scoping systematic review.General hospital psychiatryArticle
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur objective was to report on the prospective outcomes in the areas of depression, quality of life, angina, and frailty in SAVR and TAVR patients with aortic stenosis undergoing aortic valve intervention.
methodsWe recruited 300 patients across 3 groups (TAVR, SAVR, and CABG) over 12 months. Depression, quality of life, frailty, and angina were assessed followed by propensity score matching.
resultsUsing logistical regression when all patient factors considered for all patients who had SAVR and TAVR, the only preoperative factors that impacted on 1 year mortality was hypertension and STS score. Quality of life improvements within each group over 12 months was significant (p value = 0.0001). Depression at 12 months between groups (p value = 0.0395) and within each group was significant (p value = 0.0073 for SAVR and 0.0001 for TAVR). Angina was most frequent in TAVR at 12 months in the QL (p = 0.0001), PL (p = 0.0007), and improvement was significant in the QL (SAVR p = 0.0010, TAVR p = 0.0001) and PL (SAVR p = 0.0002), TAVR p = 0.0007) domains in both groups. Frailty at 12 months improved in both groups, but was greatest in TAVR (p value = 0.00126).
conclusionsThis 12 months follow up of cardiac surgical patients has revealed significant improvement in PROMs and frailty in all groups by 3 months postoperative regardless of surgical or transcatheter approach. Outcome measures of quality of life and frailty could be utilized as a measure of outcome more regularly in patients undergoing aortic valve surgery regardless of approach.
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Registered trials
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