Evidence map›Paper›PMID 35545760›Full record

ArticleBMC ophthalmology2022

High prevalence of myopia and low hyperopia reserve in 4411 Chinese primary school students and associated risk factors.

Yu Yue, Xianmao Liu, Shu Yi, Bo Liu, Hong Yi, Hong Li

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. The application of artificial intelligence in myopia prediction for children and adolescents: a review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
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  7. Identifying and Managing Pre-Myopia: A Narrative Review.Clinical ophthalmology (Auckland, N.Z.) · 2026
    Review
  8. Article
  9. IMI-2025 Digest.Investigative ophthalmology & visual science · 2025
    Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Innovative myopic screening platform based on smartphones.Frontiers in bioengineering and biotechnology · 2025
    Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yu Yue *Department of Ophthalmology, Chongqing Key Laboratory of Ophthalmology, First Affiliated Hospital of Chongqing Medical University, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, 1 Youyi Road, Chongqing, 400016, China.
Xianmao Liu *Department of Ophthalmology, Chongqing Key Laboratory of Ophthalmology, First Affiliated Hospital of Chongqing Medical University, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, 1 Youyi Road, Chongqing, 400016, China.
Shu YiDepartment of Ophthalmology, Chongqing General Hospital, University of Chinese Academy of Sciences, 104 Pipashan Road, Chongqing, 400014, China.
Bo LiuDepartment of Ophthalmology, Southwest Hospital, Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Hong YiDepartment of Ophthalmology, Chongqing General Hospital, University of Chinese Academy of Sciences, 104 Pipashan Road, Chongqing, 400014, China. yihongln@163.com.
Hong LiDepartment of Ophthalmology, Chongqing Key Laboratory of Ophthalmology, First Affiliated Hospital of Chongqing Medical University, Chongqing Eye Institute, Chongqing Branch of National Clinical Research Center for Ocular Diseases, 1 Youyi Road, Chongqing, 400016, China. lihongcqmu@163.com.
Chongqing Medical University · CNUniversity of Chinese Academy of Sciences · CNArmy Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the prevalence of myopia in Chinese primary school students and their ocular biometrics including axial length (AL), corneal radius of curvature (CRC) and spherical equivalent refraction (SER). To analyze their association with potential myopia risk factors, such as body mass index (BMI), cram school, time of outdoor activity and electronic screen use.

methodsIn this cross-sectional study of 4500 primary school students from 5 schools, participants underwent refraction using non-cycloplegic autorefractor and visual acuity testing. A follow-up study in the same schools was conducted in 2022. Myopia was defined as SER ≤ -0.50 diopter (D) and uncorrected visual acuity (UCVA) < 0.00 logMAR (6/6). Logistic regression models were used to determine factors associated with myopia.

resultsAfter excluding 389 participants, the overall prevalence of myopia was 33.6%. The prevalence of high myopia was 0.6%. The prevalence of myopia in girls was significantly higher than that in boys (37.6% vs. 30.0%, p < 0.001). The height, weight and BMI were significantly associated with AL (r = 0.471, r = 0.440, r = 0.276, p < 0.001, respectively). AL/CRC ratio was more highly correlated with SER than AL alone. Regression analysis showed that AL/CRC and hyperopia reserve were associated with myopia onset in the subsequent year (F = 201.557, p < 0.001; F = 68.934, p < 0.001). The cut point of hyperopia reserve for myopia in the subsequent year for grade 1 students was + 0.31D. Age (p < 0.001), parental myopia (p = 0.001) and lack of outdoor activity between classes (p = 0.049) were independently associated with higher prevalence rates of myopia.

conclusionThe prevalence of myopia among Chinese schoolchildren is alarming high. Consistent with previous cross-sectional data, AL/CRC and hyperopia reserve could function as myopia detection indicators. The hyperopia reserve among children aged between 6 ~ 7 years was low. Healthcare providers need to raise parents' awareness of the importance of regular eye examination and proper optical correction.

Indexed as

HyperopiaMyopiaChildChinaCorneaCross-Sectional StudiesFemaleFollow-Up StudiesHumansMalePrevalenceRefraction, OcularRisk FactorsSchoolsStudentsMyopiaOcular biometricsPrevalenceRisk factors

Identifiers

PMID35545760
PMCPMC9092685
OpenAlexW4280543952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.