Evidence map›Paper›PMID 35545677›Full record

ArticleNature2022

Revival of light signalling in the postmortem mouse and human retina.

Fatima Abbas, Silke Becker, Bryan W Jones, Ludovic S Mure, Satchidananda Panda, Anne Hanneken, Frans Vinberg

Open access · greenAbstract read
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Vascular regeneration and blood flow recovery in glaucoma.Frontiers in cell and developmental biology · 2026
    Review
  9. Article
  10. Article
  11. Advances and therapeutic opportunities in visual cycle modulation.Progress in retinal and eye research · 2025
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. A circuit motif for color in the human foveal retina.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Modeling complex age-related eye disease.Progress in retinal and eye research · 2024
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Fatima AbbasJohn A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.ORCID http://orcid.org/0000-0002-9833-5153
Silke BeckerJohn A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.ORCID http://orcid.org/0000-0003-4674-6011
Bryan W JonesJohn A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.ORCID http://orcid.org/0000-0001-5527-6643
Ludovic S MureSalk Institute for Biological Studies, La Jolla, CA, USA.
Satchidananda PandaSalk Institute for Biological Studies, La Jolla, CA, USA.
Anne HannekenDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA. ahanneke@scripps.edu.
Frans VinbergJohn A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA. frans.vinberg@utah.edu.ORCID http://orcid.org/0000-0003-3439-4979
University of Utah · USSalk Institute for Biological Studies · USScripps Research Institute · USUniversity of Bern · CH

Funding

Scripps Translational Science InstituteUL1TR002550 · NCATS · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2018 to 2022
$28.9M
University of Utah, Core Vision Research GrantP30EY014800 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Bryan William Jones · 2005 to 2026
$14.6M
Retinal RemodelingR01EY015128 · NEI · UNIVERSITY OF UTAH · PI JONES, BRYAN WILLIAM · 2004 to 2021
$7.0M
Impact of Time-Restricted Feeding (TRF) on Glucose Homeostasis and Mitochondrial Function in Patients with Metabolic SyndromeR01DK118278 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Pam Rajendran Taub · 2018 to 2026
$5.3M
Retinal CircuitryR01EY028927 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Bryan William Jones · 2019 to 2026
$5.2M
Pharmacological targeting of circadian clock components to treat glioblastomaR01CA236352 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI PANDA, SATCHIDANANDA · 2019 to 2023
$2.6M
Diurnal rhythm in nutrient metabolism for metabolic homeostasisR01DK115214 · NIDDK · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI PANDA, SATCHIDANANDA · 2018 to 2020
$2.5M
Pigment Regeneration Mechanisms in the Human RetinaR01EY031706 · NEI · UNIVERSITY OF UTAH · PI Frans Vinberg · 2020 to 2026
$2.5M
NCATS NIH HHS UL1 TR002550NCI NIH HHS R01 CA236352NEI NIH HHS P30 EY014800NEI NIH HHS R01 EY015128NEI NIH HHS R01 EY028927NEI NIH HHS R01 EY031706NIDDK NIH HHS R01 DK115214NIDDK NIH HHS R01 DK118278
6 · The paper itself

Abstract

Death is defined as the irreversible cessation of circulatory, respiratory or brain activity. Many peripheral human organs can be transplanted from deceased donors using protocols to optimize viability. However, tissues from the central nervous system rapidly lose viability after circulation ceases

Indexed as

Light Signal TransductionNeurological RehabilitationPostmortem ChangesRetinaAnimalsAutopsyCell DeathCentral Nervous SystemHumansMacacaMiceTime Factors

Identifiers

PMID35545677
PMCPMC10000337
OpenAlexW4280512127

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.