ArticleNature2022
Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17.
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 124 papers.
0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed
25.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
124 citing papers in PubMed, 196 citations in OpenAlex.
- Rethinking the Oligodendrocyte Progenitor Cell: One Cell, Many Functions.The European journal of neuroscience · 2026Review
- Ablation of the choroid plexus attenuates hydrocephalus-induced parenchymal edema with moderate reduction of postnatal hippocampal neurogenesis.Fluids and barriers of the CNS · 2026Article
- Lactoferrin and zinc sulfate supplementation alleviate cisplatin-induced taste disorder: underlying mechanisms via taste and immune modulation.NPJ science of food · 2026Article
- Oligodendroglial TANGO2 Regulates Lipid Metabolism to Control Motor Coordination.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Non-invasive characterization of perivascular subarachnoid spaces.Nature communications · 2026Article
- Could the cognitive benefits of amyloid-beta clearance grow in time for Alzheimer's disease?Translational psychiatry · 2026Review
- Article
- Apolipoprotein D, a Novel Ligand for CD36, Is Essential for Blood-Brain Barrier Integrity.Circulation · 2026Article
- Choroid plexus modulates subventricular zone adult neurogenesis and olfaction through secretion of small extracellular vesicles.Fluids and barriers of the CNS · 2026Article
- FGF family in health and disease.Molecular biomedicine · 2026Review
- Molecular Characteristics of the Endometrium in Polycystic Ovary Syndrome with Insulin Resistance.Reproductive sciences (Thousand Oaks, Calif.) · 2026Article
- ACSS2 maintains oligodendrocyte progenitor cell pool and is required for myelination during development and aging.Nature aging · 2026Article
- Hypothalamic malate dehydrogenase 2 modulates systemic glucose metabolism through oxytocin-mediated thermogenesis.Cell reports. Medicine · 2026Article
- Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition.Immunity · 2026Article
- Periodic Therapeutic Phlebotomy Mitigates Systemic Aging Phenotypes by Promoting Bone Marrow Function.Aging cell · 2026Article
- CD38 Inhibition Ameliorates Age-Related CognitiveDecline via a Choroid Plexus-Cerebrospinal Fluid-Hippocampus Axis.Research square · 2026Article
- Region-Specific Adult Neural Stem Cell Niches of the Mediobasal Hypothalamus and Medulla Oblongata.Stem cell reviews and reports · 2026Review
- Choroid Plexus Modulates Subventricular Zone Adult Neurogenesis and Olfaction Through Secretion of Small Extracellular Vesicles.Research square · 2025Article
- FGFs/FGFRs and neuroinflammatory diseases: mechanism, drug therapies and delivery systems.Journal of advanced research · 2025Review
- Control of aging-associated neurodegeneration via hypothalamic extracellular vesicles containing parathymosin.Cell reports · 2025Article
64 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
21 authors at 5 institutions in 4 countries.
Tal IramDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA. tal.iram@stanford.edu.
Fabian KernDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-8223-3750
Achint KaurDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Saket MyneniDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-9484-2617
Allison R MorningstarDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-3857-0450
Heather ShinDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Miguel A GarciaDepartment of Neurosurgery, Stanford University School of Medicine, Palo Alto, CA, USA.
Lakshmi YerraPalo Alto Veterans Institute for Research, Palo Alto, CA, USA.
Robert PalovicsDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Andrew C YangDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-6756-4746
Oliver HahnDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Nannan LuDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Steven R ShukenDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Michael S HaneyDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Benoit LehallierDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Manasi IyerDepartment of Neurosurgery, Stanford University School of Medicine, Palo Alto, CA, USA.
Jian LuoDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-2064-8467
Henrik ZetterbergDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.ORCID http://orcid.org/0000-0003-3930-4354
Andreas KellerDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.
J Bradley ZucheroDepartment of Neurosurgery, Stanford University School of Medicine, Palo Alto, CA, USA.
Tony Wyss-CorayDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA. twc@stanford.edu.ORCID http://orcid.org/0000-0001-5893-0831
Neurosciences Institute · USStanford University · USHelmholtz Institute for Pharmaceutical Research Saarland · DEPalo Alto Veterans Institute for Research · USSahlgrenska University Hospital · SE
Funding
Training in Basic Research on Aging and Age-Related DiseaseT32AG000266 · NIA · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI Lisa M Ellerby · 1998 to 2026
$13.8MTargeting CD22 to Restore Brain Homeostasis in Alzheimer's DiseaseRF1AG064897 · NIA · STANFORD UNIVERSITY · PI WYSS-CORAY, TONY · 2019 to 2019
$2.9MHow Does Actin Disassembly Drive Myelin Wrapping?R01NS119823 · NINDS · STANFORD UNIVERSITY · PI ZUCHERO, JOHN B · 2020 to 2024
$2.1MHow Does 3' UTR Secondary Structure Program mRNA Transport in Myelination?R21NS123533 · NINDS · STANFORD UNIVERSITY · PI ZUCHERO, JOHN B · 2021 to 2021
$433kEuropean Research CouncilNIA NIH HHS RF1 AG064897NIA NIH HHS T32 AG000266NINDS NIH HHS R01 NS119823NINDS NIH HHS R21 NS123533
Abstract
Recent understanding of how the systemic environment shapes the brain throughout life has led to numerous intervention strategies to slow brain ageing
Indexed as
AgingBrainCerebrospinal FluidOligodendrocyte Precursor CellsOligodendrogliaAnimalsCell DifferentiationFibroblast Growth FactorsGene Expression RegulationMiceFgf17 protein, mouseFibroblast Growth Factors
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.