Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
[Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors at 7 institutions in 1 country.
Tiffany Love *Department of Psychiatry, University of Utah & Huntsman Mental Health Institute, Salt Lake City, UT, 84112, USA.
Andrey A Shabalin *Department of Psychiatry, University of Utah & Huntsman Mental Health Institute, Salt Lake City, UT, 84112, USA.
Rachel L KemberDepartment of Psychiatry, Perelman School of Medicine at the University of Pennsylvania and Mental Illness Research, Education and Clinical Center, Crescenz VAMC, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0001-8820-2659
Anna R DochertyDepartment of Psychiatry, University of Utah & Huntsman Mental Health Institute, Salt Lake City, UT, 84112, USA.
Vincent KoppelmansDepartment of Psychiatry, University of Utah & Huntsman Mental Health Institute, Salt Lake City, UT, 84112, USA.ORCID http://orcid.org/0000-0003-2036-7603
Emily HartwellDepartment of Psychiatry, Perelman School of Medicine at the University of Pennsylvania and Mental Illness Research, Education and Clinical Center, Crescenz VAMC, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0002-5137-9714
Jacob DubroffDepartment of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA.
Jon-Kar ZubietaDepartment of Psychiatry, Northwell Health, John T. Mather Memorial Hospital, Port Jefferson, NY, 11777, USA. jzubieta1@northwell.edu.
Henry R KranzlerDepartment of Psychiatry, Perelman School of Medicine at the University of Pennsylvania and Mental Illness Research, Education and Clinical Center, Crescenz VAMC, Philadelphia, PA, 19104, USA. kranzler@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0002-1018-0450
University of Pennsylvania · USUniversity of Utah · USYale University · USDuke University · USNorthwell Health · USPhiladelphia VA Medical Center · USVirginia Commonwealth University · US
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
Radiochemistry CoreP30DA046345 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI KRANZLER, HENRY RICHARD, MACH, ROBERT H · 2019 to 2023
$9.4M
Genome-Wide Association Analysis of Suicide DeathR01MH123619 · NIMH · UNIVERSITY OF UTAH · PI DOCHERTY, ANNA R. · 2020 to 2024
$3.2M
Interaction of Smoking and Chronic Pain at Neurochemical and Phenotypic LevelsR01DA027494 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZUBIETA, JON-KAR · 2009 to 2014
$2.6M
Neurochemistry of Opiate Abuse Risk in Chronic PainR01DA022520 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZUBIETA, JON-KAR · 2006 to 2012
$2.2M
Predicting Placebo Responses Across Disease StatesR01MH086858 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZUBIETA, JON-KAR · 2009 to 2012
$1.2M
Neurochemical mediation of placebo responses in humansR01AT001415 · NCCIH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZUBIETA, JON-KAR · 2003 to 2006
$1.2M
The influence of nicotinic hepatic metabolism on neuroreceptor substrates of nicotine addictionK23DA038726 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI DUBROFF, JACOB · 2016 to 2020
$964k
Defining and manipulating social neural systems in alcohol use disorderK01AA024167 · NIAAA · UNIVERSITY OF UTAH · PI LOVE, TIFFANY · 2015 to 2019
$805k
Mu Opioid Mediated Stress Regulation in BPDR21MH069612 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZUBIETA, JON-KAR · 2004 to 2006
$549k
Characterizing the phenotypic spectrum associated with genetic liability for alcohol use disorderK01AA028292 · NIAAA · UNIVERSITY OF PENNSYLVANIA · PI KEMBER, RACHEL LORRAINE · 2021 to 2024
Major depressive disorder (MDD) and opioid use disorder (OUD) are common, potentially fatal, polygenic disorders that are moderately heritable and often co-occur. We examined the unique and shared associations of polygenic risk scores (PRS) for these disorders with µ-opioid receptor (MOR) concentration and endogenous opioid response during a stressful stimulus. Participants were 144 healthy European-ancestry (EA) subjects (88 females) who underwent MOR quantification scans with [
Indexed as
Major Depressive DisorderOpioid-Related DisordersAnalgesics, OpioidDepressionFemaleHumansMultifactorial InheritanceOpioid PeptidesAnalgesics, OpioidOpioid Peptides
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Unique and joint associations of polygenic risk for major depression and opioid use disorder with endogenous opioid system function. · full record | OpenQuestion