ArticleNPJ digital medicine2022
Effect of self-managed lifestyle treatment on glycemic control in patients with type 2 diabetes.
Article in NPJ digital medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04691973 (Evaluation of the Digital Health and Lifestyle Tool), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Digital Health and Lifestyle Tool
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Expression and mechanistic roles of long non-coding RNAs in diabetic cataract: a systematic review and meta-analysis.Biology direct · 2026Pooled it
- Smartphone-delivered multicomponent lifestyle medicine intervention for improving mental health in a nonclinical population: a randomized controlled trial.Frontiers in public health · 2023Trial
- Patient Perspectives on Quantified Self Technologies and Healthcare Costs Among Patients with Diabetes in Zimbabwe.International journal of environmental research and public health · 2026Article
- Patient-specific deep offline artificial pancreas for blood glucose regulation in type 1 diabetes.Smart health (Amsterdam, Netherlands) · 2026Article
- Preventive measures for Parkinson's disease: insights into motivation and barriers from the patients' perspective.BMC neurology · 2026Article
- Comparison of the Efficacy of Type 2 Diabetes Group Training Courses With and Without the Integration of mHealth Support in a Controlled Trial Setting: Results of a Comparative Pilot Study.Diabetes spectrum : a publication of the American Diabetes Association · 2025Article
- Harnessing Digital Initiatives for Improved Health Outcomes in Diabetes Management: An Observational Patient Program.Cureus · 2024Article
- Long-term effects of a telemedically-assisted lifestyle intervention on glycemic control in patients with type 2 diabetes - A two-armed randomised controlled trial in Germany.Journal of diabetes and metabolic disorders · 2024Article
- Nutrient patterns and risk of diabetes mellitus type 2: a case-control study.BMC endocrine disorders · 2024Article
- Article
- Diabetic Pneumopathy- A Novel Diabetes-associated Complication: Pathophysiology, the Underlying Mechanism and Combination Medication.Endocrine, metabolic & immune disorders drug targets · 2024Review
- Digital lifestyle treatment improves long-term metabolic control in type 2 diabetes with different effects in pathophysiological and genetic subgroups.NPJ digital medicine · 2023Article
- Digital innovations for retinal care in diabetic retinopathy.Acta diabetologica · 2022Review
- Formative Qualitative Research: Design Considerations for a Self-Directed Lifestyle Intervention for Type-2 Diabetes Patients Using Human-Centered Design Principles in Benin.International journal of environmental research and public health · 2022Article
- What Intervention Elements Drive Weight Loss in Blended-Care Behavior Change Interventions? A Real-World Data Analysis with 25,706 Patients.Nutrients · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The lack of effective, scalable solutions for lifestyle treatment is a global clinical problem, causing severe morbidity and mortality. We developed a method for lifestyle treatment that promotes self-reflection and iterative behavioral change, provided as a digital tool, and evaluated its effect in 370 patients with type 2 diabetes (ClinicalTrials.gov identifier: NCT04691973). Users of the tool had reduced blood glucose, both compared with randomized and matched controls (involving 158 and 204 users, respectively), as well as improved systolic blood pressure, body weight and insulin resistance. The improvement was sustained during the entire follow-up (average 730 days). A pathophysiological subgroup of obese insulin-resistant individuals had a pronounced glycemic response, enabling identification of those who would benefit in particular from lifestyle treatment. Natural language processing showed that the metabolic improvement was coupled with the self-reflective element of the tool. The treatment is cost-saving because of improved risk factor control for cardiovascular complications. The findings open an avenue for self-managed lifestyle treatment with long-term metabolic efficacy that is cost-saving and can reach large numbers of people.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.