Evidence map›Paper›PMID 35545411›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2022

High levels of platelet

Li Huang, Chanjuan Shen, Yong Zhong, Joshua D Ooi, Peter J Eggenhuizen, Ya'ou Zhou, Jinbiao Chen, Ting Wu, Ting Meng, Zhou Xiao and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Li HuangDepartment of Critical Care Medicine, Xiangya Hospital, Central South University, Changsha 410008. 617068207@qq.com.
Chanjuan ShenDepartment of Hematology, Affiliated Zhuzhou Hospital Xiangya Medical College, Central South University, Zhuzhou Hunan 412007.
Yong ZhongDepartment of Nephrology, Xiangya Hospital, Central South University, Changsha 410008. zhongyong121@163.com.
Joshua D OoiCentre for Inflammatory Diseases, Monash University, Clayton, Victoria 3168, Australia.
Peter J EggenhuizenCentre for Inflammatory Diseases, Monash University, Clayton, Victoria 3168, Australia.
Ya'ou ZhouDepartment of Rheumatology and Immunology, Xiangya Hospital, Central South University, Changsha 410008.
Jinbiao ChenDepartment of Medical Records & Information, Xiangya Hospital, Central South University, Changsha 410008.
Ting WuDepartment of Nephrology, Xiangya Hospital, Central South University, Changsha 410008.
Ting MengDepartment of Nephrology, Xiangya Hospital, Central South University, Changsha 410008.
Zhou XiaoDepartment of Nephrology, Xiangya Hospital, Central South University, Changsha 410008.
Wei LinDepartment of Pathology, Xiangya Hospital, Central South University, Changsha 410008, China.
Rong TangDepartment of Nephrology, Xiangya Hospital, Central South University, Changsha 410008.
Xiang AoDepartment of Nephrology, Xiangya Hospital, Central South University, Changsha 410008.
Xiangcheng XiaoDepartment of Nephrology, Xiangya Hospital, Central South University, Changsha 410008.
Qiaoling ZhouDepartment of Nephrology, Xiangya Hospital, Central South University, Changsha 410008.
Ping XiaoDepartment of Nephrology, Xiangya Hospital, Central South University, Changsha 410008.

Funding

the Key Research and Development Program of Hunan province 2020WK2008the Natural Science Foundation of Hunan Province 2021JJ31130 and 2020JJ5903the Talent Scholars of Hunan Province for the Innovation of Science and Technology 2020RC5002
6 · The paper itself

Abstract

objectivesPlatelet-to-lymphocyte ratio (PLR) has recently been investigated as a new inflammatory marker in many inflammatory diseases, including systemic lupus erythematosus and immunoglobulin A vasculitis. However, there were very few reports regarding the clinical role of PLR in patients with anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis. This study was thus undertaken to investigate the relationship between inflammatory response and disease activity in Chinese patients with myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) associated vasculitis. Furthermore, we evaluated whether PLR predicts the progression of end stage of renal disease (ESRD) and all-cause mortality.

methodsThe clinical, laboratory and pathological data, and the outcomes of MPO-ANCA associated vasculitis patients were collected. The Spearman correlation coefficient was computed to examine the association between 2 continuous variables. Cox regression analysis was used to estimate the association between PLR and ESRD or all-cause mortality.

resultsA total of 190 consecutive patients with MPO-ANCA associated vasculitis were included in this study. Baseline PLR was positively correlated with CRP (

conclusionsPLR is positively correlated with CRP and ESR. Furthermore, PLR may independently predict the risk of ESRD.

Indexed as

Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisKidney Failure, ChronicAntibodies, Antineutrophil CytoplasmicChinaHumansLymphocytesPeroxidaseRetrospective StudiesAntibodies, Antineutrophil CytoplasmicPeroxidaseanti-neutrophil cytoplasmic antibody-associated vasculitisend stage of renal diseasemortalitymyeloperoxidaseplatelet-to-lymphocyte ratio

Identifiers

PMID35545411
PMCPMC10930527

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.