Evidence map›Paper›PMID 35545394›Full record

ArticleBMJ open2022

Qualitative study of patient experiences and care observations during agitation events in the emergency department: implications for systems-based practice.

Ambrose H Wong, Jessica M Ray, Christopher Eixenberger, Lauren J Crispino, John B Parker, Alana Rosenberg, Leah Robinson, Caitlin McVaney, Joanne DeSanto Iennaco, Steven L Bernstein and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  3. Association between patient primary language, physical restraints, and intramuscular sedation in the emergency department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025
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  6. Racial, Ethnic, and Age-Related Disparities in Sedation and Restraint Use for Older Adults in the Emergency Department.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Ambrose H WongDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA wongambrose@gmail.com.ORCID 0000-0001-7471-1647
Jessica M RayDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0003-3410-1507
Christopher EixenbergerDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Lauren J CrispinoDepartment of Emergency Medicine, Virginia Tech Carilion Clinic, Roanoke, Virginia, USA.
John B ParkerDepartment of Emergency Medicine, Coliseum Health System, Macon, Georgia, USA.
Alana RosenbergYale School of Public Health, New Haven, Connecticut, USA.ORCID 0000-0003-4695-5745
Leah RobinsonYale School of Public Health, New Haven, Connecticut, USA.
Caitlin McVaneyDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Joanne DeSanto IennacoDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.
Steven L BernsteinDepartment of Emergency Medicine, Dartmouth-Hitchcock Health System, Lebanon, New Hampshire, USA.ORCID 0000-0002-9964-7036
Kimberly A YonkersDepartment of Psychiatry, University of Massachusetts Medical School, Worchester, Massachusetts, USA.
Anthony J PavloDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.
Yale University · USCarilion Clinic · USDartmouth–Hitchcock Medical Center · USNavicent Health · USUniversity of Massachusetts Chan Medical School · US

Funding

Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
Implementation of Decision Support for the Management of Obesity in a National Pediatric Primary Care Research NetworkR01MD014853 · NIMHD · YALE UNIVERSITY · PI SHARIFI, MAHNOOSH · 2020 to 2024
$3.9M
Clinical Decision Support Tool to Assess Risk and Prevent Agitation EventsK23MH126366 · NIMH · YALE UNIVERSITY · PI WONG, AMBROSE H · 2021 to 2024
$883k
AHRQ HHS R01 HS028340NCATS NIH HHS KL2 TR001862NIMHD NIH HHS R01 MD014853NIMH NIH HHS K23 MH126366
6 · The paper itself

Abstract

objectivesAgitation, defined as excessive psychomotor activity leading to aggressive or violent behaviour, is prevalent in the emergency department (ED) due to rising behavioural-related visits. Experts recommend use of verbal de-escalation and avoidance of physical restraint to manage agitation. However, bedside applications of these recommendations may be limited by system challenges in emergency care. This qualitative study aims to use a systems-based approach, which considers the larger context and system of healthcare delivery, to identify sociotechnical, structural, and process-related factors leading to agitation events and physical restraint use in the ED.

designQualitative study using a grounded theory approach to triangulate interviews of patients who have been physically restrained with direct observations of agitation events.

settingTwo EDs in the Northeast USA, one at a tertiary care academic centre and the other at a community-based teaching hospital.

participantsWe recruited 25 individuals who experienced physical restraint during an ED visit. In addition, we performed 95 observations of clinical encounters of agitation events on unique patients. Patients represented both behavioural (psychiatric, alcohol/drug use) and non-behavioural (medical, trauma) chief complaints.

resultsThree primary themes with implications for systems-based practice of agitation events in the ED emerged: (1) pathways within health and social systems; (2) interpersonal contexts as reflections of systemic stressors on behavioural emergency care and (3) systems-based and patient-oriented strategies and solutions.

conclusionsAgitation events represented manifestations of patients' structural barriers to care from socioeconomic inequities and high burden of emotional and physical trauma as well as staff members' simultaneous exposure to external stressors from social and healthcare systems. Potential long-term solutions may include care approaches that recognise agitated patients' exposure to psychological trauma, improved coordination within the mental health emergency care network, and optimisation of physical environment conditions and organisational culture.

Indexed as

Emergency Service, HospitalRestraint, PhysicalAggressionHumansPatient Outcome AssessmentPsychomotor AgitationQualitative Researchemergency medicinehealthcare systempsychomotor agitationqualitative research

Identifiers

PMID35545394
PMCPMC9096567
OpenAlexW4280615662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.