Evidence map›Paper›PMID 35545321›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2022

High efficiency of left superior frontal gyrus and the symptom features of major depressive disorder.

Liang Zhang, Zexuan Li, Xiaowen Lu, Jin Liu, Yumeng Ju, Qiangli Dong, Jinrong Sun, Mi Wang, Bangshan Liu, Jiang Long and 7 more

Open access · greenAbstract read
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Liang ZhangDepartment of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011. 148201021@csu.edu.cn.
Zexuan LiDepartment of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011.
Xiaowen LuDepartment of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011.
Jin LiuDepartment of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011.
Yumeng JuDepartment of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011.
Qiangli DongDepartment of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011.
Jinrong SunDepartment of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011.
Mi WangDepartment of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011.
Bangshan LiuDepartment of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011.
Jiang LongShanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine, Shanghai 200030.
Yan ZhangDepartment of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011.
Qiang XuDepartment of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210000.
Weihui LiDepartment of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011.
Xiang LiuDepartment of Industrial Engineering, Tsinghua University, Beijing 100084.
Hua GuoZhumadian Second People's Hospital, Zhumadian Henan 463000, China.
Guangming LuDepartment of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210000.
Lingjiang LiDepartment of Psychiatry, Second Xiangya Hospital, Central South University, Changsha 410011. llj2920@csu.edu.cn.
Central South University · CNNanjing Medical University · CNShanghai Mental Health Center · CNTsinghua University · CNZhumadian Central Hospital · CN

Funding

the National Key R&D Program 2019YFA0706200the National Natural Science Foundation 91232714
6 · The paper itself

Abstract

objectivesMajor depressive disorder (MDD) patients with anhedonia tend to have a poor prognosis. The underlying imaging basis for anhedonia in MDD remains largely unknown. The relationship between nodal properties and anhedonia in MDD patients need to be further investigated. Herein, this study aims to explore differences of cerebral functional node characteristics in MDD patients with severe anhedonia (MDD-SA) and MDD patients with mild anhedonia (MDD-MA) before and after the antidepressant treatment.

methodsNinety participants with current MDD were recruited in this study. 24-Item Hamilton Depression Scale (HAMD-24) and Snaith-Hamilton Pleasure Scale (SHAPS) were used to assess the severity of depression and anhedonia at baseline and the end of 6-months treatment. The MDD patients who scored above the 25th percentile on the SHAPS were assigned to an MDD-SA group (

resultsRepeated measures 2-factor ANCOVA showed significant main effects on group on the e

conclusionsThere are obvious differences in nodal properties between the MDD-SA and the MDD-MA patients, such as the high e

Indexed as

Major Depressive DisorderAnhedoniaAntidepressive AgentsHumansInfantInfant, NewbornMagnetic Resonance ImagingPrefrontal CortexAntidepressive Agentsanhedoniafunctional magnetic resonance imagingmajor depressive disordernodal network

Identifiers

PMID35545321
PMCPMC10930058
OpenAlexW4280516260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.