Evidence map›Paper›PMID 35545221›Full record

ArticleKidney research and clinical practice2022

The importance of muscle mass in predicting intradialytic hypotension in patients undergoing maintenance hemodialysis.

Hyung Eun Son, Ji Young Ryu, Kyunghoon Lee, Young Il Choi, Myeong Sung Kim, Inwhee Park, Gyu Tae Shin, Heungsoo Kim, Curie Ahn, Sejoong Kim and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Kidney research and clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 12 citations in OpenAlex.

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  6. Review
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  11. Sarcopenia in chronic kidney disease: from bench to bedside.The Korean journal of internal medicine · 2023
    Review
  12. Article
  13. Review
  14. Healthy aging and chronic kidney disease.Kidney research and clinical practice · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Hyung Eun SonDivision of Nephrology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Ji Young RyuDivision of Nephrology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Kyunghoon LeeDepartment of Laboratory Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Young Il ChoiChoi's Medical Clinic, Suwon, Republic of Korea.
Myeong Sung KimGojan Myeong Internal Medicine Clinic, Ansan, Republic of Korea.
Inwhee ParkDivision of Nephrology, Department of Internal Medicine, Ajou University Hospital, Suwon, Republic of Korea.
Gyu Tae ShinDivision of Nephrology, Department of Internal Medicine, Ajou University Hospital, Suwon, Republic of Korea.
Heungsoo KimDivision of Nephrology, Department of Internal Medicine, Ajou University Hospital, Suwon, Republic of Korea.
Curie AhnDivision of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Sejoong KimDivision of Nephrology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Ho Jun ChinDivision of Nephrology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Ki Young NaDivision of Nephrology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Dong-Wan ChaeDivision of Nephrology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Soyeon AhnMedical Research Collaborating Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Seung Sik HwangDepartment of Public Health Science, School of Public Health, Seoul National University, Seoul, Republic of Korea.
Jong Cheol JeongDivision of Nephrology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Seoul National University · KRSeoul National University Bundang Hospital · KRAjou University Hospital · KR

Funding

Seoul National University Bundang Hospital 02-2020-026
6 · The paper itself

Abstract

backgroundPatients undergoing hemodialysis are susceptible to sarcopenia. As intracellular reservoirs of water, skeletal muscles are important contributors to intradialytic hypotension. This study was designed to determine the role of skeletal muscle mass in intradialytic hypotension.

methodsIn a cross-sectional study, the body composition of 177 patients was measured immediately after hemodialysis using bioelectrical impedance analysis. The parameters measured were skeletal muscle mass, intracellular and extracellular water contents, total body water, and cell-membrane functionality (in phase angle at 50 kHz). Data from laboratory tests, chest radiography, measurements of handgrip strength and mid-arm circumference, and questionnaires were collected. The main outcome was intradialytic hypotension, defined as more than two episodes of hypotension (systolic blood pressure of <90 mmHg) with intervention over the 3 months following enrollment. Logistic regression models including each parameter related to sarcopenia were compared with a clinical model.

resultsPatients with a low ratio of skeletal muscle mass to dry body weight (SMM/WT) had a higher rate of intradialytic hypotension (40.7%). Most low-SMM/WT patients were female, obese, diabetic, and had a lower handgrip strength compared with the other patients. In the high-SMM/WT group, the risk of intradialytic hypotension was lower, with an odds ratio of 0.08 (95% confidence interval [CI], 0.02-0.28) and adjusted odds ratio of 0.06 (95% CI, 0.01-0.29).

conclusionMeasurement and maintenance of skeletal muscle can help prevent intradialytic hypotension in frail patients undergoing hemodialysis.

Indexed as

Body compositionHypotensionRenal dialysisSarcopenia

Identifiers

PMID35545221
PMCPMC9576459
OpenAlexW4280594475

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.