Evidence map›Paper›PMID 35545215›Full record

ArticleClinical endoscopy2022

Does computer-aided diagnostic endoscopy improve the detection of commonly missed polyps? A meta-analysis.

Arun Sivananthan, Scarlet Nazarian, Lakshmana Ayaru, Kinesh Patel, Hutan Ashrafian, Ara Darzi, Nisha Patel

Abstract read
In one paragraph

Article in Clinical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. [Role of Artificial Intelligence in Improving Quality of Colonoscopy].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
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  10. Eye tracking technology in endoscopy: Looking to the future.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2023
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arun SivananthanInstitute of Global Health Innovation, Imperial College, London, UK.
Scarlet NazarianInstitute of Global Health Innovation, Imperial College, London, UK.
Lakshmana AyaruDepartment of Surgery and Cancer, Imperial College NHS Healthcare Trust, London, UK.
Kinesh PatelDepartment of Gastroenterology, Chelsea and Westminster NHS Healthcare Trust, London, UK.
Hutan AshrafianInstitute of Global Health Innovation, Imperial College, London, UK.
Ara DarziInstitute of Global Health Innovation, Imperial College, London, UK.
Nisha PatelInstitute of Global Health Innovation, Imperial College, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsColonoscopy is the gold standard diagnostic method for colorectal neoplasia, allowing detection and resection of adenomatous polyps; however, significant proportions of adenomas are missed. Computer-aided detection (CADe) systems in endoscopy are currently available to help identify lesions. Diminutive (≤5 mm) and nonpedunculated polyps are most commonly missed. This meta-analysis aimed to assess whether CADe systems can improve the real-time detection of these commonly missed lesions.

methodsA comprehensive literature search was performed. Randomized controlled trials evaluating CADe systems categorized by morphology and lesion size were included. The mean number of polyps and adenomas per patient was derived. Independent proportions and their differences were calculated using DerSimonian and Laird random-effects modeling.

resultsSeven studies, including 2,595 CADe-assisted colonoscopies and 2,622 conventional colonoscopies, were analyzed. CADe-assisted colonoscopy demonstrated an 80% increase in the mean number of diminutive adenomas detected per patient compared with conventional colonoscopy (0.31 vs. 0.17; effect size, 0.13; 95% confidence interval [CI], 0.09-0.18); it also demonstrated a 91.7% increase in the mean number of nonpedunculated adenomas detected per patient (0.32 vs. 0.19; effect size, 0.05; 95% CI, 0.02-0.07).

conclusionCADe-assisted endoscopy significantly improved the detection of most commonly missed adenomas. Although this method is a potentially exciting technology, limitations still apply to current data, prompting the need for further real-time studies.

Indexed as

Artificial intelligenceColonoscopyColorectal neoplasmsComputer-aided detection

Identifiers

PMID35545215
PMCPMC9178131

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.