Evidence map›Paper›PMID 35544640›Full record

ArticleScience advances2022

H3K4me3 recognition by the COMPASS complex facilitates the restoration of this histone mark following DNA replication.

Albert Serra-Cardona, Shoufu Duan, Chuanhe Yu, Zhiguo Zhang

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

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  11. Inheritance of epigenetic transcriptional memory.Current opinion in genetics & development · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Albert Serra-CardonaInstitute for Cancer Genetics, Department of Pediatrics and Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA.ORCID 0000-0003-0282-7311
Shoufu DuanInstitute for Cancer Genetics, Department of Pediatrics and Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA.ORCID 0000-0003-0416-374X
Chuanhe YuThe Hormel Institute, University of Minnesota, Austin, MN 55912, USA.ORCID 0000-0003-1885-7224
Zhiguo ZhangInstitute for Cancer Genetics, Department of Pediatrics and Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA.ORCID 0000-0002-9451-2685
Cancer Genetics (United States) · USUniversity of Minnesota · US

Funding

Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Parisa Tehranifar · 1985 to 2026
$115.3M
Mechanisms of Epigenetic inheritanceR35GM118015 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Zhiguo Zhang · 2016 to 2026
$9.5M
Role of nucleosome dynamics in epigenetic inheritanceR01GM130588 · NIGMS · UNIVERSITY OF MINNESOTA · PI YU, CHUANHE · 2019 to 2023
$1.7M
Mechanisms for histone segregation at DNA replication forks and implications for epigenetic inheritance.K99GM134180 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SERRA CARDONA, ALBERT · 2019 to 2020
$200k
NCI NIH HHS P30 CA013696NIGMS NIH HHS K99 GM134180NIGMS NIH HHS R01 GM130588NIGMS NIH HHS R35 GM118015
6 · The paper itself

Abstract

During DNA replication, parental H3-H4 marked by H3K4me3 are transferred almost equally onto leading and lagging strands of DNA replication forks. Mutations in replicative helicase subunit, Mcm2 (Mcm2-3A), and leading strand DNA polymerase subunit, Dpb3 (

Indexed as

Histone CodeHistonesDNADNA ReplicationDNAhistone H3 trimethyl Lys4Histones

Identifiers

PMID35544640
PMCPMC9075808
OpenAlexW4229023840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.