Evidence map›Paper›PMID 35544562›Full record

ArticleScience advances2022

A bioactive phlebovirus-like envelope protein in a hookworm endogenous virus.

Monique Merchant, Carlos P Mata, Yangci Liu, Haoming Zhai, Anna V Protasio, Yorgo Modis

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Monique MerchantMolecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.ORCID 0000-0002-6783-7193
Carlos P MataMolecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.ORCID 0000-0003-3381-7431
Yangci LiuMolecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.ORCID 0000-0001-8843-3529
Haoming ZhaiMolecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
Anna V ProtasioDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.ORCID 0000-0003-1723-800X
Yorgo ModisMolecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.ORCID 0000-0002-6084-0429
MRC Laboratory of Molecular Biology · GBUniversity of Cambridge · GB

Funding

The structural basis of nucleic acid recognition by Toll-like receptorsR01GM102869 · NIGMS · YALE UNIVERSITY · PI MODIS, YORGO · 2012 to 2015
$1.1M
NIGMS NIH HHS R01 GM102869Wellcome Trust 217191
6 · The paper itself

Abstract

Endogenous viral elements (EVEs), accounting for 15% of our genome, serve as a genetic reservoir from which new genes can emerge. Nematode EVEs are particularly diverse and informative of virus evolution. We identify Atlas virus-an intact retrovirus-like EVE in the human hookworm

Indexed as

PhlebovirusRNA VirusesAncylostomatoideaAnimalsHumansViral Envelope ProteinsViral Fusion ProteinsVirus InternalizationViral Envelope ProteinsViral Fusion Proteins

Identifiers

PMID35544562
PMCPMC9094657
OpenAlexW4280510985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.