Evidence map›Paper›PMID 35544461›Full record

ArticlePloS one2022

PVP1-The People's Ventilator Project: A fully open, low-cost, pressure-controlled ventilator research platform compatible with adult and pediatric uses.

Julienne LaChance, Manuel Schottdorf, Tom J Zajdel, Jonny L Saunders, Sophie Dvali, Chase Marshall, Lorenzo Seirup, Ibrahim Sammour, Robert L Chatburn, Daniel A Notterman and 1 more

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. TWINKLE: An open-source two-photon microscope for teaching and research.bioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Data science and its future in large neuroscience collaborations.bioRxiv : the preprint server for biology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Julienne LaChanceDepartment of Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey, United States of America.
Manuel SchottdorfPrinceton Neuroscience Institute, Princeton University, Princeton, New Jersey, United States of America.ORCID 0000-0002-5468-4255
Tom J ZajdelDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America.ORCID 0000-0002-7957-3180
Jonny L SaundersDepartment of Psychology and Institute of Neuroscience, University of Oregon, Eugene, Oregon, United States of America.
Sophie DvaliDepartment of Physics, Princeton University, Princeton, New Jersey, United States of America.
Chase MarshallRailPod, Inc., Boston, Massachusetts, United States of America.
Lorenzo SeirupNew York ISO, Rensselaer, New York, United States of America.
Ibrahim SammourDepartment of Neonatology, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, United States of America.
Robert L ChatburnDepartment of Neonatology, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, United States of America.
Daniel A NottermanDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America.
Daniel J CohenDepartment of Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey, United States of America.

Funding

NRSA TrainingTL1TR003019 · NCATS · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI SCOTTO, KATHLEEN W. · 2019 to 2023
$1.9M
NCATS NIH HHS TL1 TR003019
6 · The paper itself

Abstract

Mechanical ventilators are safety-critical devices that help patients breathe, commonly found in hospital intensive care units (ICUs)-yet, the high costs and proprietary nature of commercial ventilators inhibit their use as an educational and research platform. We present a fully open ventilator device-The People's Ventilator: PVP1-with complete hardware and software documentation including detailed build instructions and a DIY cost of $1,700 USD. We validate PVP1 against both key performance criteria specified in the U.S. Food and Drug Administration's Emergency Use Authorization for Ventilators, and in a pediatric context against a state-of-the-art commercial ventilator. Notably, PVP1 performs well over a wide range of test conditions and performance stability is demonstrated for a minimum of 75,000 breath cycles over three days with an adult mechanical test lung. As an open project, PVP1 can enable future educational, academic, and clinical developments in the ventilator space.

Indexed as

Intensive Care UnitsVentilators, MechanicalAdultChildHumansRespiration, Artificial

Identifiers

PMID35544461
PMCPMC9094548

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.