Evidence map›Paper›PMID 35544281›Full record

ArticleThe American journal of clinical nutrition2022

Association between postterm pregnancy and adverse growth outcomes in preschool-age children.

Jun Tang, Wanglong Gou, Yuanqing Fu, Kelei Li, Xiaofei Guo, Tao Huang, Huijuan Liu, Duo Li, Ju-Sheng Zheng

Open access · greenAbstract read
In one paragraph

Article in The American journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Association of Gestational Age in a Full Range With Childhood Overweight and Obesity: A Systematic Scoping Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jun TangKey Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.
Wanglong GouKey Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.
Yuanqing FuKey Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.ORCID 0000-0002-3955-9376
Kelei LiInstitute of Nutrition and Health, Qingdao University, Qingdao, China.
Xiaofei GuoInstitute of Nutrition and Health, Qingdao University, Qingdao, China.
Tao HuangDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Huijuan LiuJiaxing University Affiliated Women and Children Hospital, Jiaxing, China.
Duo LiInstitute of Nutrition and Health, Qingdao University, Qingdao, China.
Ju-Sheng ZhengKey Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.ORCID 0000-0001-6560-4890
Westlake University · CNQingdao University · CNJiaxing University · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostterm pregnancy has been associated with higher risk of perinatal mortality and morbidity, but its long-term health effects on offspring are poorly understood.

objectivesThe aim of the study was to investigate the prospective associations between maternal postterm pregnancy and adverse growth outcomes in children.

methodsThe Jiaxing Birth Cohort is part of a large population-based health surveillance system in China and recruited pregnant females resident in the Jiaxing area between 1999 and 2013; newborns were followed up for a median duration of 5.8 y until they went to school. Mother-child pairs with maternal gestational information and offspring's anthropometric data at 4-7 y old were included. Postterm pregnancy was defined as maternal gestational age ≥42 and <47 wk, and its associations with offspring obesity, overweight/obesity, and thinness during childhood were determined by using Poisson regression models.

resultsOf the 101,505 included mother-child pairs, 2369 (2.3%) children were born at postterm. Children born at postterm had significantly lower BMI-for-age z score, weight-for-age z score, and height-for-age z score than those born at term; the mean difference (95% CI) was -0.11 (-0.15, -0.06), -0.17 (-0.21, -0.13), and -0.16 (-0.20, -0.12), respectively. When comparing postterm with term pregnancy, the multivariable-adjusted RRs and 95% CIs among preschool-age children were 0.87 (0.68, 1.11) for obesity, 0.82 (0.72, 0.94) for overweight/obesity, and 1.18 (1.09, 1.28) for thinness, respectively. These risk estimates were robust in sensitivity analyses, but were attenuated in several subgroups stratified by age, sex, mode of delivery, and fetal distress.

conclusionsPostterm pregnancy was associated with a higher risk of thinness, and a lower risk of overweight/obesity, as well as lower growth parameters in preschool-age children. These findings imply that postterm pregnancy may impede the long-term growth of offspring.

Indexed as

OverweightPediatric ObesityBirth WeightBody HeightBody Mass IndexChild, PreschoolFemaleHumansInfant, NewbornObesityPregnancyThinnessbirth cohortchildrengrowth outcomesoverweight/obesitypostterm pregnancythinness

Identifiers

PMID35544281
PMCPMC9348988
OpenAlexW4280635623

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.