Evidence map›Paper›PMID 35543774›Full record

ReviewBrain informatics2022

Smart imaging to empower brain-wide neuroscience at single-cell levels.

Shuxia Guo, Jie Xue, Jian Liu, Xiangqiao Ye, Yichen Guo, Di Liu, Xuan Zhao, Feng Xiong, Xiaofeng Han, Hanchuan Peng

Abstract readReview
In one paragraph

Review in Brain informatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shuxia Guo *Institute for Brain and Intelligence, Southeast University, Nanjing, 210096, Jiangsu, China. shuxia_guo@seu.edu.cn.ORCID http://orcid.org/0000-0001-8237-8936
Jie Xue *Institute for Brain and Intelligence, Southeast University, Nanjing, 210096, Jiangsu, China.
Jian LiuInstitute for Brain and Intelligence, Southeast University, Nanjing, 210096, Jiangsu, China.
Xiangqiao YeInstitute for Brain and Intelligence, Southeast University, Nanjing, 210096, Jiangsu, China.
Yichen GuoInstitute for Brain and Intelligence, Southeast University, Nanjing, 210096, Jiangsu, China.
Di LiuInstitute for Brain and Intelligence, Southeast University, Nanjing, 210096, Jiangsu, China.
Xuan ZhaoInstitute for Brain and Intelligence, Southeast University, Nanjing, 210096, Jiangsu, China.
Feng XiongInstitute for Brain and Intelligence, Southeast University, Nanjing, 210096, Jiangsu, China.
Xiaofeng HanInstitute for Brain and Intelligence, Southeast University, Nanjing, 210096, Jiangsu, China. xfhan@seu.edu.cn.
Hanchuan PengInstitute for Brain and Intelligence, Southeast University, Nanjing, 210096, Jiangsu, China.

Funding

Fundamental Research Funds for the Central Universities 2242022R10037National Natural Science Foundation of China 21773028
6 · The paper itself

Abstract

A deep understanding of the neuronal connectivity and networks with detailed cell typing across brain regions is necessary to unravel the mechanisms behind the emotional and memorial functions as well as to find the treatment of brain impairment. Brain-wide imaging with single-cell resolution provides unique advantages to access morphological features of a neuron and to investigate the connectivity of neuron networks, which has led to exciting discoveries over the past years based on animal models, such as rodents. Nonetheless, high-throughput systems are in urgent demand to support studies of neural morphologies at larger scale and more detailed level, as well as to enable research on non-human primates (NHP) and human brains. The advances in artificial intelligence (AI) and computational resources bring great opportunity to 'smart' imaging systems, i.e., to automate, speed up, optimize and upgrade the imaging systems with AI and computational strategies. In this light, we review the important computational techniques that can support smart systems in brain-wide imaging at single-cell resolution.

Indexed as

Artificial intelligenceBrain-wideNeuroscienceSingle-cellSmart imaging

Identifiers

PMID35543774
PMCPMC9095808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.