Evidence map›Paper›PMID 35543673›Full record

ArticleBlood transfusion = Trasfusione del sangue2023

Influence of user-centered clinical decision support on pediatric blood product ordering errors.

Evan W Orenstein, Margo Rollins, Jennifer Jones, Swaminathan Kandaswamy, Jeanne Boudreaux, Alexis B Carter, Cassandra D Josephson

Open access · greenAbstract read
In one paragraph

Article in Blood transfusion = Trasfusione del sangue, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Evan W OrensteinDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States of America.
Margo RollinsDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States of America.
Jennifer JonesAflac Cancer and Blood Disorders Program, Children's Healthcare of Atlanta, Atlanta, GA, United States of America.
Swaminathan KandaswamyDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States of America.
Jeanne BoudreauxDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States of America.
Alexis B CarterDepartment of Pathology and Laboratory Medicine, Children's Healthcare of Atlanta, Atlanta, GA, United States of America.
Cassandra D JosephsonDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, United States of America.
Emory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren are at increased risk from transfusion-related medical errors. Clinical decision support (CDS) can enhance pediatric providers' decision-making regarding transfusion practices including indications, volume, rate, and special processing instructions. Our objective was to use CDS in a pediatric health system to reduce:blood product-related safety events from ordering errors;special processing ordering errors for patients with T-cell dysfunction, sickle cell disease (SCD), or thalassemia;transfusions administered faster than 5 mL/kg/h. MATERIALS AND

methodsIn this single-center before and after quality improvement study, we evaluated how user-centered design of pediatric blood product orders influenced pediatric transfusion practices and outcomes. Safety events were identified through active and passive surveillance. Other clinically relevant outcomes were identified through electronic health record queries.

resultsBlood product-related safety events from ordering errors did not change significantly from the baseline period (6 events, 0.4 per month, from 1/1/2018-3/27/2019) to the intervention period (1 event, 0.1 per month, from 3/28/2019-12/31/2019; rate ratio: 0.27 [0.01-2.25]). Packed red blood cell (PRBC) and platelet orders for patients with T-cell dysfunction that did not specify irradiation decreased significantly from 488/12,359 (3.9%) to 204/6,711 (3.0%, risk ratio: 0.77 [0.66-0.90]). PRBC orders for patients with SCD or thalassemia that did not specify phenotypically similar units fell from 386/2,876 (13.4%) to 57/1,755 (3.2%, risk ratio: 0.24 [0.18-0.32]). Transfusions administered faster than 5 mL/kg/h decreased from 4,112/14,641 (28.1%) to 2,125/9,263 (22.9%, risk ratio: 0.82 [0.78-0.85]). DISCUSSION: User-centered design of CDS for pediatric blood product orders significantly reduced special processing ordering errors and inappropriate transfusion rates. Larger studies are needed to evaluate the impact on safety events.

Indexed as

Anemia, Sickle CellDecision Support Systems, ClinicalThalassemiaBlood PlateletsBlood TransfusionChildHumans

Identifiers

PMID35543673
PMCPMC9918378
OpenAlexW4280641648

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.