Evidence map›Paper›PMID 35543382›Full record

ArticleClinical transplantation2022

Heart transplant recipient 1-year outcomes during the COVID-19 pandemic.

Gabriel Esmailian, Nikhil Patel, Jignesh K Patel, Lawrence Czer, Matthew Rafiei, Dominick Megna, Dominic Emerson, Danny Ramzy, Alfredo Trento, Joanna Chikwe and 2 more

Open access · greenAbstract read
In one paragraph

Article in Clinical transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Gabriel EsmailianThe George Washington University School of Medicine and Health Sciences, Washington DC, USA.ORCID 0000-0002-1820-7910
Nikhil PatelCedars-Sinai Smidt Heart Institute, Los Angeles, California, USA.
Jignesh K PatelCedars-Sinai Smidt Heart Institute, Los Angeles, California, USA.
Lawrence CzerCedars-Sinai Smidt Heart Institute, Los Angeles, California, USA.
Matthew RafieiCedars-Sinai Smidt Heart Institute, Los Angeles, California, USA.
Dominick MegnaCedars-Sinai Smidt Heart Institute, Los Angeles, California, USA.
Dominic EmersonCedars-Sinai Smidt Heart Institute, Los Angeles, California, USA.
Danny RamzyCedars-Sinai Smidt Heart Institute, Los Angeles, California, USA.
Alfredo TrentoCedars-Sinai Smidt Heart Institute, Los Angeles, California, USA.
Joanna ChikweCedars-Sinai Smidt Heart Institute, Los Angeles, California, USA.
Fardad EsmailianCedars-Sinai Smidt Heart Institute, Los Angeles, California, USA.
Jon A KobashigawaCedars-Sinai Smidt Heart Institute, Los Angeles, California, USA.
Cedars-Sinai Smidt Heart Institute · USGeorge Washington University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic initially brought forth considerable challenges to the field of heart transplantation. To prevent the spread of the virus and protect immunocompromised recipients, our center made the following modifications to post-transplant outpatient management: eliminating early coronary angiograms, video visits for postoperative months 7, 9, and 11, and home blood draws for immunosuppression adjustments. To assess if these changes have impacted patient outcomes, the current study examines 1-year outcomes for patients transplanted during the pandemic. Between March and September 2020, we assessed 50 heart transplant patients transplanted during the pandemic. These patients were compared to patients who were transplanted during the same months between 2011 and 2019 (n = 482). Endpoints included subsequent 1-year survival, freedom from cardiac allograft vasculopathy, any-treated rejection, acute cellular rejection, antibody-mediated rejection, nonfatal major adverse cardiac events (NF-MACE), and hospital and ICU length of stay. Patients transplanted during the pandemic had similar 1-year endpoints compared to those of patients transplanted from years prior apart from 1-year freedom from NF-MACE which was significantly higher for patients transplanted during the pandemic. Despite necessary changes being made to outpatient management of heart transplant recipients, heart transplantation continues to be safe and effective with similar 1-year outcomes to years prior.

Indexed as

COVID-19Heart TransplantationGraft RejectionHumansPandemicsRetrospective StudiesTransplant RecipientsCOVID-19heart transplantationpandemicSARS-CoV-2

Identifiers

PMID35543382
PMCPMC9348427
OpenAlexW4280568777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.