ArticleESC heart failure2022
Prognostic significance of serum potassium in patients hospitalized for acute heart failure.
Article in ESC heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Potassium levels and the risk of all-cause and cardiovascular mortality among patients with cardiovascular diseases: a meta-analysis of cohort studies.Nutrition journal · 2024Pooled it
- Biomarkers in heart failure: Traditional and emerging indicators for prognosis.ESC heart failure · 2025Article
- Electrolyte Levels in Poor Prognosis and Early Neurological Deterioration in Patients With Acute Ischemic Stroke.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- 2024 update in heart failure.ESC heart failure · 2025Review
- Association of Potassium Level at Discharge with Long-Term Mortality in Hospitalized Patients with Heart Failure.Journal of clinical medicine · 2022Article
- Heart failure: an update from the last years and a look at the near future.ESC heart failure · 2022Review
- Prognostic significance of serum potassium in patients hospitalized for acute heart failure.ESC heart failure · 2022Article
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Authors and funding
11 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimWe investigated the prognostic significance of serum potassium abnormalities at discharge in patients hospitalized for acute heart failure (AHF). METHODS AND
resultsIn a retrospective analysis, we included 926 patients hospitalized for AHF, stratified by serum potassium levels at discharge as hypokalaemia (<3.5 mEq/L), normokalaemia (3.5-5.0 mEq/L), and hyperkalaemia (>5.0 mEq/L). The primary endpoint was all-cause death at 1 year since hospital discharge. At discharge, 40 patients had hypokalaemia (4.3%), 840 normokalaemia (90.7%), and 46 hyperkalaemia (5.0%). Patients with hyperkalaemia at discharge were more frequently men, had more signs of congestion, and lower LVEF while patients with hypokalaemia were more likely to be women with HFpEF. Treatment with ACEi/ARBs and MRAs ≥50% of target dose at discharge was similar across groups. One year all-cause death occurred in 10% of the patients with hypokalaemia, 13.9% of those with normokalaemia, and 30.4% of those with hyperkalaemia (P = 0.006). After adjustment for covariates, including renal function, background treatment, and baseline potassium level, hyperkalaemia resulted an independent predictor of the primary endpoint (HR 1.96, 95% IC [1.01-3.82]; P = 0.048).
conclusionsIn patients with AHF, the presence of hyperkalaemia at discharge is an independent predictor of 1 year all-cause death.
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