Evidence map›Paper›PMID 35543182›Full record

ArticleTopics in stroke rehabilitation2023

Incidence of post-stroke depression symptoms and potential risk factors in adults with aphasia in a comprehensive stroke center.

Christina Zanella, Jacqueline Laures-Gore, Vonetta M Dotson, Samir R Belagaje

Open access · greenAbstract read
In one paragraph

Article in Topics in stroke rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Factors Related to Depression Symptoms in Chronic Poststroke Aphasia.Archives of physical medicine and rehabilitation · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
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  12. Stroke-associated dysarthria.Frontiers in neurology · 2025
    Review
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  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Link between post-stroke psychopathology and scope-of-action awareness.Therapeutic advances in neurological disorders · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Christina ZanellaGerontology Institute, Georgia State University, Atlanta, GA, USA.
Jacqueline Laures-GoreDepartment of Communication Sciences and Disorders, Georgia State University, Atlanta, GA, USA.
Vonetta M DotsonDepartment of Psychology and Gerontology Institute, Georgia State University, Atlanta, GA, USA.
Samir R BelagajeDepartments of Neurology and Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Georgia State University · USEmory University · US

Funding

CSF, MRI, and PET biomarkers of neuroinflammation in Alzheimer's diseaseR01AG054046 · NIA · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI HU, WILLIAM TZU-LUNG · 2016 to 2020
$3.9M
NIA NIH HHS R01 AG054046
6 · The paper itself

Abstract

introductionDepression may be a frequent sequela after stroke, however, its incidence has rarely been reported. The likelihood of post-stroke depression (PSD) may relate to individual factors including the presence of aphasia, which also complicates PSD diagnosis. The current study's purpose was to investigate the incidence of PSD symptoms in adults with aphasia, compare it to the incidence of PSD symptoms in adults without aphasia, and to identify potential risk factors for developing PSD in adults with aphasia.

methodIncidence proportions and relative risk were calculated using data compiled from 970 patient records at an urban tertiary care academic institution and comprehensive stroke center throughout the year of 2019. Focusing exclusively on adults with aphasia, the selected variables of age, gender, race, and aphasia severity were used to conduct logistic regression analyses to explore potential risk factors contributing to the development of PSD.

resultsAdults with aphasia were 7.408 times more likely to exhibit PSD symptoms than adults without aphasia. Logistic regression controlling for the presence of aphasia showed a significant relationship between aphasia severity and post-stroke depression symptoms. Adults with aphasia were 2.06 times more likely to experience post-stroke depression symptoms with every 1-point increase in aphasia severity.

conclusionsThese findings align with earlier evidence identifying aphasia as a risk factor for experiencing PSD symptoms and also suggest aphasia severity is proportionate to the risk. This highlights the need for early identification of PSD symptoms in persons with aphasia in order to provide timely interventions.

Indexed as

AphasiaStrokeAdultDepressionHumansIncidenceRisk FactorsAphasiaincidencePatient Health Questionnairepost-stroke depressionrisk factors

Identifiers

PMID35543182
PMCPMC9649834
OpenAlexW4280528197

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.