Evidence map›Paper›PMID 35543103›Full record

ArticleAntimicrobial agents and chemotherapy2022

Frieder Fuchs, Alexander Maximilian Aldejohann, Ada Marie Hoffmann, Grit Walther, Oliver Kurzai, Axel G Hamprecht

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Nitroxoline exerts potent anti-Antimicrobial agents and chemotherapy · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The multidrug-resistantCurrent research in microbial sciences · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Frontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Frieder FuchsInstitute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Medical faculty and University Hospital of Cologne, Cologne, Germany.ORCID 0000-0001-7075-5378
Alexander Maximilian AldejohannInstitute for Hygiene and Microbiology, University Wuerzburg, Wuerzburg, Germany.
Ada Marie HoffmannInstitute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Medical faculty and University Hospital of Cologne, Cologne, Germany.
Grit WaltherNational Reference Center for Invasive Fungal Infections (NRZMyk), Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.
Oliver KurzaiInstitute for Hygiene and Microbiology, University Wuerzburg, Wuerzburg, Germany.ORCID 0000-0002-7277-2646
Axel G HamprechtInstitute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Medical faculty and University Hospital of Cologne, Cologne, Germany.ORCID 0000-0003-1449-5780
Institute of Medical Microbiology and Hygiene · DEUniversity of Cologne · DECarl von Ossietzky Universität Oldenburg · DELeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections by drug-resistant fungi are increasingly reported worldwide; however, only few novel antifungals are being developed. The old antimicrobial nitroxoline is currently repurposed for oral treatment of bacterial urinary tract infections (UTI). Previously, antifungal activity has been demonstrated and in contrast to many antifungals nitroxoline reaches high urinary concentrations. In this study, the activity of nitroxoline was assessed

Indexed as

Urinary TractUrinary Tract InfectionsAntifungal AgentsCandidaDrug Resistance, FungalEscherichia coliFluconazoleHumansMicrobial Sensitivity TestsNitroquinolinesAntifungal AgentsFluconazoleNitroquinolinesnitroxoline8-hydroxyquinolineazoleazole-nonsusceptibleCandida aurisCandida glabratacandiduriamultidrug resistancequinolinesurinary tract infectionyeast

Identifiers

PMID35543103
PMCPMC9211423
OpenAlexW4280610258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.