ArticleRSC advances2019
A theoretical study of the radical scavenging activity of natural stilbenes.
Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 48 citations in OpenAlex.
- Electrochemical and Computational Studies Show That Vitamin C Assists Resveratrol, Piceatannol and Oxyresveratrol in Superoxide Scavenging, Suggesting a Superoxide Dismutase Mechanism.International journal of molecular sciences · 2026Article
- Theoretical Insight into Antioxidant Mechanisms of Trans-Isoferulic Acid in Aqueous Medium at Different pH.International journal of molecular sciences · 2025Article
- Evaluation of antioxidant properties of lycopene isomers using density functional theory.Journal of molecular modeling · 2025Article
- The scavenging mechanism of hydrazone compounds towards HOO˙ and CHRSC advances · 2025Article
- Theoretical Insight into Antioxidant Mechanism of Caffeic Acid Against Hydroperoxyl Radicals in Aqueous Medium at Different pH-Thermodynamic and Kinetic Aspects.International journal of molecular sciences · 2024Article
- Insights into antiradical mechanism and pro-oxidant enzyme inhibitor activity of walterolactone A/B 6-RSC advances · 2022Article
- Current Trends in Computational Quantum Chemistry Studies on Antioxidant Radical Scavenging Activity.Journal of chemical information and modeling · 2022Review
- The hydroperoxyl antiradical activity of natural hydroxycinnamic acid derivatives in physiological environments: the effects of pH values on rate constants.RSC advances · 2022Article
- Oxoberberine: a promising natural antioxidant in physiological environments.RSC advances · 2022Article
- Theoretical insights into the antiradical activity and copper-catalysed oxidative damage of mexidol in the physiological environment.Royal Society open science · 2022Article
- The radical scavenging activity of muriolide in physiological environments: mechanistic and kinetic insights into double processes.RSC advances · 2021Article
- The hydroperoxyl radical scavenging activity of sulfuretin: insights from theory.Royal Society open science · 2021Article
- Article
- Is natural fraxin an overlooked radical scavenger?RSC advances · 2021Article
- Isosmotic Macrocation Variation Modulates Mineral Efficiency, Morpho-Physiological Traits, and Functional Properties in Hydroponically Grown Lettuce Varieties (Frontiers in plant science · 2021Article
- Comparison of the scavenging capacities of phloroglucinol and 2,4,6-trihydroxypyridine towards HO˙ radical: a computational study.RSC advances · 2020Article
- Article
- The radical scavenging activity of moracins: theoretical insights.RSC advances · 2020Article
- Article
- Protective Effects of Some Grapevine Polyphenols against Naturally Occurring Neuronal Death.Molecules (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress is implicated in aging and aging-related diseases, including cancer. Prevention-focused health management approaches emphasize the importance of dietary antioxidants, which naturally draws attention to the antioxidant capacity of natural products. Several groups of plant-derived antioxidant compounds have been identified and their radical scavenging activity confirmed and measured; it has proven challenging, however, to link the experimentally determined activity quantitatively to a molecular mechanism of action. Based on our success with a computational approach, in this study, the methylperoxyl radical scavenging activity of 12 natural stilbenes was evaluated based on kinetic and thermodynamic calculations. The results suggest that for stilbenes hydrogen atom transfer (HAT) is a main mechanism for the ROO˙ radical scavenging in the gas. Assessing the role of substitutes on the antioxidant properties of stilbenes revealed that the presence of O-H groups in ring B can increase the antioxidant activity due to a decrease in the bond dissociation energy (BDE) of the O4'-H, while the replacement of a H atom in the O-H groups by a methyl group reduces the radical scavenging capacity. Among the studied compounds, astringin is a promising antioxidant with the low BDE(O-H) value (73.4 kcal mol
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.