ReviewRSC advances2018
Biological properties of calcium phosphate biomaterials for bone repair: a review.
Review in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 198 citations in OpenAlex.
- Applications of DNA Hydrogels in Osteoporotic Bone Defects.Journal of functional biomaterials · 2026Review
- Silver-Doped Mesoporous Calcium Phosphate for Controlled Amoxicillin Delivery and Modulation of Osteoblast-like Cell Response.Pharmaceutics · 2026Article
- Wear, fatigue characteristics, and antibacterial performance of UHMWPE reinforced with HAP+TiOScientific reports · 2026Article
- Calcium Phosphate Nanostructured Biocomposites with Applications in Bone Tissue Engineering.Materials (Basel, Switzerland) · 2026Review
- Effect of thin porous ceramic coatings on implant stability: a comparative study of GB14 and β-TCP with and without Cu.Journal of materials science. Materials in medicine · 2026Article
- Ultra-thin porous calcium phosphate coatings show extensive remodeling and high osseointegration after 24 weeks in a rabbit femoral condyle model.Frontiers in bioengineering and biotechnology · 2026Article
- Preparation and characterization of bio-waste derived chitosan/hydroxyapatite/pectin green biocomposite.Scientific reports · 2025Article
- Radiographical Assessment of Injectable Calcium Phosphate Bone Cement (Osteopaste) in Critical Size Bone Defects of Rabbit's Tibia Model.Malaysian orthopaedic journal · 2025Article
- Electro-spun piezoelectric PLLA smart composites as a scaffold on bone fracture: A review.Regenerative therapy · 2025Review
- Research status of biomaterials based on physical signals for bone injury repair.Regenerative therapy · 2025Review
- Stannous Fluoride in Toothpastes: A Review of Its Clinical Effects and Likely Mechanisms of Action.Journal of functional biomaterials · 2025Review
- Impact of the Applied Electrode System on Properties of Electrodeposited Calcium Phosphate Coatings.Materials (Basel, Switzerland) · 2025Article
- Exploring the Biological Impact of β-TCP Surface Polarization on Osteoblast and Osteoclast Activity.International journal of molecular sciences · 2024Article
- Comparison Between Nano-Hydroxyapatite/Beta-Tricalcium Phosphate Composite and Autogenous Bone Graft in Bone Regeneration Applications: Biochemical Mechanisms and Morphological Analysis.International journal of molecular sciences · 2024Article
- Clinical efficacy on the reconstruction of bone defects using modular hemipelvic prosthesis in patients with pelvic tumors.Journal of orthopaedic surgery and research · 2024Article
- Magnesium-Doped Hydroxyapatite Nanofibers for Medicine Applications: Characterization, Antimicrobial Activity, and Cytotoxicity Study.International journal of molecular sciences · 2024Article
- Chemically Pretreated Densification of Juniper Wood for Potential Use in Osteosynthesis Bone Implants.Journal of functional biomaterials · 2024Article
- Review
- Large-Scale Green Synthesis of Magnesium Whitlockite from Environmentally Benign Precursor.Materials (Basel, Switzerland) · 2024Article
- Amorphous, Carbonated Calcium Phosphate and Biopolymer-Composite-Coated SiNanomaterials (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bone defects are a common disease threatening the health of many people. Calcium phosphate (CaP) is an ideal bone substitutive material that is widely used for bone repair due to its excellent biological properties including osteoinductivity, osteoconductivity and biodegradability. For this reason, investigation of these properties and the effects of various influencing factors is vital for modulating calcium phosphate during the design process to maximally satisfy clinical requirements. In this study, the latest studies on the biological properties of CaP biomaterials, including hydroxyapatite (HA), tricalcium phosphate (TCP), and biphasic calcium phosphate (BCP), have been summarized. Moreover, recent advances on how these properties are altered by different factors are reviewed. Considering the limited mechanical strength of CaP materials, this study also reviews CaP composites with different materials as improvement measures. Finally, perspectives regarding future developments of CaP materials are also provided.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.