Evidence map›Paper›PMID 35542469›Full record

ArticleRSC advances2018

Revealing biomedically relevant cell and lectin type-dependent structure-activity profiles for glycoclusters by using tissue sections as an assay platform.

Herbert Kaltner, Joachim C Manning, Gabriel García Caballero, Claudia Di Salvo, Adele Gabba, Laura L Romero-Hernández, Clemens Knospe, Dan Wu, Harrison C Daly, Donal F O'Shea and 2 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Herbert KaltnerInstitute of Physiological Chemistry, Faculty of Veterinary Medicine, Ludwig-Maximilians-University Munich Veterinärstr. 13 80539 Munich Germany.
Joachim C ManningInstitute of Physiological Chemistry, Faculty of Veterinary Medicine, Ludwig-Maximilians-University Munich Veterinärstr. 13 80539 Munich Germany.
Gabriel García CaballeroInstitute of Physiological Chemistry, Faculty of Veterinary Medicine, Ludwig-Maximilians-University Munich Veterinärstr. 13 80539 Munich Germany.
Claudia Di SalvoSchool of Chemistry, National University of Ireland Galway University Road Galway Ireland paul.v.murphy@nuigalway.ie.
Adele GabbaSchool of Chemistry, National University of Ireland Galway University Road Galway Ireland paul.v.murphy@nuigalway.ie.
Laura L Romero-HernándezSchool of Chemistry, National University of Ireland Galway University Road Galway Ireland paul.v.murphy@nuigalway.ie.
Clemens KnospeInstitute of Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Ludwig-Maximilians-University Munich Veterinärstr. 13 80539 Munich Germany.ORCID https://orcid.org/0000-0002-9183-0231
Dan WuDepartment of Chemistry, Royal College of Surgeons of Ireland (RCSI) 123 St. Stephen's Green Dublin 2 Ireland.
Harrison C DalyDepartment of Chemistry, Royal College of Surgeons of Ireland (RCSI) 123 St. Stephen's Green Dublin 2 Ireland.
Donal F O'SheaDepartment of Chemistry, Royal College of Surgeons of Ireland (RCSI) 123 St. Stephen's Green Dublin 2 Ireland.ORCID https://orcid.org/0000-0003-0594-4193
Hans-Joachim GabiusInstitute of Physiological Chemistry, Faculty of Veterinary Medicine, Ludwig-Maximilians-University Munich Veterinärstr. 13 80539 Munich Germany.
Paul V MurphySchool of Chemistry, National University of Ireland Galway University Road Galway Ireland paul.v.murphy@nuigalway.ie.ORCID https://orcid.org/0000-0002-1529-6540
University of Veterinary Medicine · HUOllscoil na Gaillimhe – University of Galway · IERoyal College of Surgeons in Ireland · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing realization of the involvement of lectin-glycan recognition in (patho)physiological processes inspires envisioning therapeutic intervention by high-avidity/specificity blocking reagents. Synthetic glycoclusters are proving to have potential for becoming such inhibitors but the commonly used assays have their drawbacks to predict

Identifiers

PMID35542469
PMCPMC9084366
OpenAlexW2885598884

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.