Evidence map›Paper›PMID 35542447›Full record

ArticleRSC advances2018

Probing the stereoselectivity of OleD-catalyzed glycosylation of cardiotonic steroids.

Xue-Lin Zhu, Chao Wen, Qing-Mei Ye, Wei Xu, Deng-Lang Zou, Guang-Ping Liang, Fan Zhang, Wan-Na Chen, Ren-Wang Jiang

Abstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xue-Lin ZhuGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University Guangzhou 510632 P. R. China trwjiang@jnu.edu.cn.ORCID https://orcid.org/0000-0003-1125-7461
Chao WenGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University Guangzhou 510632 P. R. China trwjiang@jnu.edu.cn.
Qing-Mei YeDepartment of Pharmacy, Hainan General Hospital Haikou 570311 P. R. China.
Wei XuGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University Guangzhou 510632 P. R. China trwjiang@jnu.edu.cn.
Deng-Lang ZouGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University Guangzhou 510632 P. R. China trwjiang@jnu.edu.cn.
Guang-Ping LiangGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University Guangzhou 510632 P. R. China trwjiang@jnu.edu.cn.
Fan ZhangGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University Guangzhou 510632 P. R. China trwjiang@jnu.edu.cn.
Wan-Na ChenGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University Guangzhou 510632 P. R. China trwjiang@jnu.edu.cn.
Ren-Wang JiangGuangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University Guangzhou 510632 P. R. China trwjiang@jnu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The glycosyltransferase OleD variant as a catalyst for the glycosylation of four pairs of epimers of cardiotonic steroids (CTS) are assessed. The results of this study demonstrated that the OleD-catalyze glycosylation of CTS is significantly influenced by the configuration at C-3 and the A/B fusion mode. 3β-OH and A/B ring

Identifiers

PMID35542447
PMCPMC9078122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.